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Uncategorized Published - 4 September, 2024    By - Dr Clemens
Promise of Remimazolam in Pediatric Emergence Delirium

Authors: Pablo M. Ingelmo, M.D.; Andrew J. Davidson, M.B.B.S., M.D. Anesthesiology September 2024, Vol. 141, 434–436. “Remimazolam was effective … in lowering the occurrence of emergence delirium … [in children and] reducing the need for propofol intervention …” Remimazolam represents an emergent class of benzodiazepine-related compounds with a faster onset and offset than midazolam, integrating features of […]

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Uncategorized Published - 4 September, 2024    By - Dr Clemens
Comparison of Differences in Cohort (Forward) and Case Control (Backward) Methodologic Approaches for Validation of the Hypotension Prediction Index

Authors: Simon J. Davies, F.R.C.A., M.D. et al  Anesthesiology September 2024, Vol. 141, 443–452. Background The Hypotension Prediction Index (the index) software is a machine learning algorithm that detects physiologic changes that may lead to hypotension. The original validation used a case control (backward) analysis that has been suggested to be biased. This study therefore conducted […]

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Uncategorized Published - 4 September, 2024    By - Dr Clemens
Anesthesia Incident Reporting System (AIRS) Case 2024-07: ChatANES

Author: Patrick Guffey, MD ASA Monitor July 2024, Vol. 88, 12. An anesthesiology resident was caring for a patient scheduled for removal of a baclofen pump due to suspected infection, and during the preoperative period the neurosurgery resident assisting on the case requested the anesthesiology resident consider an appropriate dose to cover until the pump was […]

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Uncategorized Published - 4 September, 2024    By - Dr Clemens
Developmental Anesthesia Neurotoxicity Research in Humans: Moving the Concept

Authors: Laszlo Vutskits, M.D., Ph.D.; Andrew J. Davidson, M.B.B.S., M.D. Anesthesiology September 2024, Vol. 141, 431–433. There are many observational studies investigating the relationship between anesthesia exposure in childhood and later neurocognitive and behavioral outcomes. In this issue of Anesthesiology, Silber et al.  report another such observational study. This study, however, is different, and the data can be interpreted […]

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Uncategorized Published - 4 September, 2024    By - Dr Clemens
Science, Medicine, and the Anesthesiologist

Anesthesiology September 2024, Vol. 141, A13–A15. Effect of early vs late inguinal hernia repair on serious adverse event rates in preterm infants: A randomized clinical trial. JAMA 2024; 331:1035–44. PMID: 38530261. Inguinal hernia repair in premature neonates is associated with morbidity, but it is controversial whether repair should be done before or after intensive care unit […]

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