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Uncategorized Published - 6 December, 2024    By - Dr Clemens
Methadone Dosing and Postoperative Pain Management in Cardiothoracic Surgery

Authors: Adam J. Milam, M.D., Ph.D. et al  Anesthesiology December 2024, Vol. 141, 1205–1207. To the Editor: Cardiac surgery is associated with significant postoperative pain. Methadone reduces postoperative pain and opioid consumption after cardiothoracic procedures, but the dosing of intraoperative methadone is unclear.  Our previous investigation of this retrospective cohort found that the use of intraoperative methadone […]

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Uncategorized Published - 6 December, 2024    By - Dr Clemens
Discover The Best Anesthesiologist Opportunity in New Mexico

We are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]

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Uncategorized Published - 6 December, 2024    By - Dr Clemens
Activation of α7 Nicotinic Acetylcholine Receptors Inhibits Hepatic Necroptosis and Ameliorates Acute Liver Injury in Mice

Authors: Fang-Fang Xu, M.S. et al  Anesthesiology December 2024, Vol. 141, 1119–1138. Background Acute liver injury is a disease characterized by severe liver dysfunction, caused by significant infiltration of immune cells and extensive cell death with a high mortality. Previous studies demonstrated that the α7 nicotinic acetylcholine receptor (α7nAChR) played a crucial role in various liver […]

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Uncategorized Published - 6 December, 2024    By - Dr Clemens
Science, Medicine, and the Anesthesiologist

Author: Martin J. London, M.D Anesthesiology December 2024, Vol. 141, A13–A15. Intraoperative oxygen treatment, oxidative stress, and organ injury following cardiac surgery: A randomized clinical trial. JAMA Surg 2024; 159:1106–16. PMID: 39110454. Liberal administration of oxygen (hyperoxia) is commonly used intraoperatively ostensibly to enhance patient safety, particularly during cardiac surgery, despite potential adverse effects on perioperative […]

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Uncategorized Published - 5 December, 2024    By - Dr Clemens
Intraoperative Vasopressors and Delirium: Reply

Authors: Haobo Ma, M.D., M.Sc., M.P.H. et al  Anesthesiology December 2024, Vol. 141, 1211–1212. In Reply: We thank Drs. Kumar and Jain1  for their interest in our study on the association between intraoperative use of phenylephrine, compared to ephedrine, and delirium after noncardiac surgery under general anesthesia. We appreciate the authors’ remarks emphasizing the importance of our […]

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