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Uncategorized Published - 30 December, 2024    By - Dr Clemens
Optimal Maternal Ventilation During Laparotomy with General Anesthesia in Pregnancy in the Ovine Model

AUTHORS: Bleeser, Tom MD, PhD et al Anesthesia & Analgesia 140(1):p 175-184, January 2025. BACKGROUND: General anesthesia during pregnancy is not uncommon, for example, for trauma surgery, cerclage, or cesarean delivery. Current recommendations are to maintain maternal partial pressure of carbon dioxide in arterial blood (paCO2) at 30 mm Hg, which is based solely on the […]

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Uncategorized Published - 27 December, 2024    By - Dr Clemens
Blood Pressure Estimation Using Explainable Deep-Learning Models Based on Photoplethysmography

AUTHORS: Perdereau, Jade MSc et al Anesthesia & Analgesia 140(1):p 119-128, January 2025. BACKGROUND: Due to their invasiveness, arterial lines are not typically used in routine monitoring, despite their superior responsiveness in hemodynamic monitoring and detecting intraoperative hypotension. To address this issue, noninvasive, continuous arterial pressure monitoring is necessary. We developed a deep-learning model that reconstructs […]

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Uncategorized Published - 27 December, 2024    By - Dr Clemens
The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients

AUTHORS: Devinney, Michael J. MD, PhD et al Anesthesia & Analgesia 140(1):p 99-109, January 2025. BACKGROUND: Obstructive sleep apnea is associated with increased dementia risk, yet its role in postoperative neurocognitive disorders is unclear. Here, we studied whether the severity of untreated obstructive sleep apnea is associated with the severity of postoperative neurocognitive disorder. METHODS: In […]

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Uncategorized Published - 27 December, 2024    By - Dr Clemens
Factors Associated With Decision to Use and Dosing of Sugammadex in Children

AUTHORS: Brown, Sydney E.S. MD, PhD et al Anesthesia & Analgesia 140(1):p 87-98, January 2025. BACKGROUND: Sugammadex was initially approved for reversal of neuromuscular blockade in adults in the United States in 2015. Limited data suggest sugammadex is widely used in pediatric anesthesia practice however the factors influencing use are not known. We explore patient, surgical, […]

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Uncategorized Published - 27 December, 2024    By - Dr Clemens
Occurrence of Low Cardiac Index During Normotensive Periods in Cardiac Surgery

AUTHORS: Goeddel, Lee A. MD, MPH et al Anesthesia & Analgesia 140(1):p 77-86, January 2025. BACKGROUND: Continuous cardiac output monitoring is not standard practice during cardiac surgery, even though patients are at substantial risk for systemic hypoperfusion. Thus, the frequency of low cardiac output during cardiac surgery is unknown. METHODS: We conducted a prospective cohort study […]

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