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Anesthesiology Published - 1 January, 2025    By - Dr Clemens
Changes in intraoperative rocuronium dosing following the introduction of sugammadex and association with postoperative respiratory complications

Authors: Wachtendorf LJ et al. Anesthesiology. December 2025. SummaryThis large retrospective cohort study examined how the introduction of sugammadex influenced intraoperative rocuronium dosing practices and whether changes in dosing were associated with postoperative respiratory complications. While sugammadex enables rapid and reliable reversal of even deep neuromuscular blockade, concerns have emerged that its availability may encourage […]

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Uncategorized Published - 1 January, 2025    By - Dr Clemens
Evaluating Large Language Model Performance in Generating Clinically Relevant Intensive Care Unit Discharge Summaries

Authors: Mudumbai SC et al. A & A Practice. 19(9):e02057, September 2025. SummaryThis study evaluated the clinical quality of large language model (LLM)–generated intensive care unit (ICU) discharge summaries compared with traditional physician-authored summaries. ICU discharge summaries are time-intensive and cognitively demanding, requiring accurate synthesis of complex, longitudinal clinical data. The authors examined whether current […]

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Uncategorized Published - 31 December, 2024    By - Dr Clemens
Mortality Prediction of Biochemical Parameters in Patients Intubated in the Emergency Department

Authors: Koca Y, Bozan Ö, Polat M, et al. Cureus 16(11): e73508. Introduction Tracheal intubation is a high-risk airway management protocol frequently applied in patients with critical illnesses. Numerous parameters have been suggested to predict mortality in these patients. Blood gas analysis, electrolyte levels, enzyme activities, and other biochemical measurements provide insights into a patient’s […]

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Uncategorized Published - 31 December, 2024    By - Dr Clemens
Effects of Sphingosine-1-Phosphate on the Facilitation of Peripheral Nerve Regeneration

Authors: Li C, Yamamoto T, Kanemaru H, et al. Cureus 16(11): e73784. Abstract This study aims to explore the role of sphingosine-1-phosphate (S1P) in peripheral nerve regeneration after injury. S1P is a crucial metabolite involved in cell migration, inflammation, and nerve regeneration. In this research, six-week-old male Sprague-Dawley rats (total n=18) underwent transection of the inferior […]

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Uncategorized Published - 31 December, 2024    By - Dr Clemens
Comparison of Intravenous Ibuprofen Versus Intravenous Ketorolac in Acute Postoperative Pain

Authors: Nair A, Bodhey A, Jabri A A, et al. Cureus 16(11): e73759. Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) are popularly used in the management of acute postoperative pain. Intravenous (IV) ketorolac has been used for several years for this purpose. Recently, IV ibuprofen has been introduced for the management of postoperative pain. This review aims to […]

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