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Anesthesiology Published - 24 March, 2026    By - Dr Clemens
The role of preoptic area GABAergic neurons in distinctly regulating sleep and rousability under dexmedetomidine sedation in mice

Authors: Qiu G et al. Anesthesiology, January 26, 2026, 10.1097/ALN.0000000000005953 This experimental neuroscience study examined how specific populations of GABAergic neurons in the preoptic area (POA) regulate sleep, wakefulness, and dexmedetomidine-induced sedation. Dexmedetomidine is unique among sedatives because it produces a form of sedation that closely resembles natural sleep and allows patients to remain easily […]

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Anesthesiology Published - 24 March, 2026    By - Dr Clemens
Professionalism Perceptions: A Comparison of Anesthesiology Trainees and Attendings

Authors: Chen F et al. Anesthesiology, February 05, 2026, 10.1097/ALN.0000000000005974 This multi-institutional study examined how anesthesiology trainees and attending physicians perceive professionalism and unprofessional conduct in clinical training environments. Professionalism is considered a core competency in graduate medical education, yet there is limited specialty-specific research examining whether trainees and faculty interpret professional behaviors differently. The […]

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Anesthesiology Published - 24 March, 2026    By - Dr Clemens
Intranasal naloxone reversal of opioid-induced respiratory depression in opioid-naïve individuals and self-reported daily opioid users

Authors: van Lemmen M A et al. Anesthesiology, February 05, 2026, 10.1097/ALN.0000000000005931 This prospective crossover trial evaluated how effectively intranasal naloxone reverses opioid-induced respiratory depression caused by potent synthetic opioids. Because current overdose deaths are frequently related to high-affinity opioids such as fentanyl and its analogs, understanding the performance of commonly used intranasal naloxone formulations […]

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Anesthesiology Published - 24 March, 2026    By - Dr Clemens
Overdose propofol emulsion induces PANoptosis in human peripheral neutrophils in an ex vivo model

Authors: Lin M-C et al. Anesthesiology, February 12, 2026, 10.1097/ALN.0000000000005978 This study explored how overdose exposure to propofol emulsion may injure human peripheral neutrophils and provides mechanistic insight relevant to propofol infusion syndrome (PRIS). PRIS is a rare but severe complication associated with excessive or prolonged propofol exposure and is typically characterized by metabolic derangements, […]

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Anesthesiology Published - 24 March, 2026    By - Dr Clemens
Reviewing Current Trends: Private Equity in Anesthesiology

Authors: Xie K et al. Anesthesiology, February 13, 2026, 10.1097/ALN.0000000000005918 This review examines the expanding role of private equity investment in anesthesiology and places it within the broader context of healthcare consolidation, financial pressures, and workforce challenges in the United States. The authors describe how the rapid growth of private equity in healthcare—now representing hundreds […]

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