Authors: Robles J, Rogando D, Ranjbar T, et al. Cureus 16(10): e70681. doi:10.7759/cureus.70681 Abstract Although rare, local anesthetic use has been associated with adverse central nervous system and cardiovascular adverse events. One complication is local anesthetic systemic toxicity (LAST), wherein the anesthetic agent inadvertently enters systemic circulation resulting in widespread inhibition of fast-gated sodium channels. Organs […]
Read MoreAuthors: Antunes B, Araújo M, Noversa C, et al. Cureus 16(10): e70667. doi:10.7759/cureus.70667 Abstract Patients with hypermobile Ehlers-Danlos syndrome (hEDS) usually present with generalized joint hypermobility and pain, soft and hyperextensible skin with atrophic scars and easy bruising, periodontitis, mitral valve prolapse, and aortic root dilation. It may also lead to cervical spine instability or […]
Read MoreAuthors: Lisa Goudman, Ph.D. et al Anesthesiology October 2024, Vol. 141, 815–816. In Reply: We appreciate the interest of Dr. Tsai et al. in our recent study of pain medication prescriptions in chronic pain and for advocating for further studies of personalized chronic pain management in clinical practice. We share the idea of the authors to start […]
Read MoreAuthors: Yolanda Yong-Yan Tsai, M.B.A. et al Anesthesiology October 2024, Vol. 141, 814–815. To the Editor: We read with interest the study by Goudman et al. titled “Incidence and Prevalence of Pain Medication Prescriptions in the Pathology of Chronic Pain,” in which the data underscored a marked increase in nonsteroidal anti-inflammatory drug (NSAID) prescription trends. This uptick mirrors the […]
Read MoreAuthors: Maxime Léger, M.D., Ph.D. et al Anesthesiology November 2024, Vol. 141, 1024–1025. In Reply: We thank Xue et al. for their interest in our study. The potential impact of opioid-free anesthesia protocols is a current topic, and the possibility that it could improve the quality of patient recovery is a promising aspect of anesthetic management. Our team […]
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