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Authors: Brandi A. Bottiger, M.D. et al Anesthesiology December 2024, Vol. 141, 1217–1218. In Reply: First, we would like to thank Strauss et al. for their insight regarding the problem of primary graft dysfunction in response to our recent clinical review article. This article correctly points out that primary graft dysfunction, or perioperative allograft injury due to […]
Read MoreAuthors: Erik R. Strauss, M.D. et al Anesthesiology December 2024, Vol. 141, 1216–1217. To the Editor: The review by Bottiger et al. highlights several recent studies related to allogenic transfusions for lung transplantation. The authors discuss perioperative factors that increase the risk of bleeding, report the evidence that connects transfusion to worse outcome, and suggest strategies to […]
Read MoreNeural circuit basis of placebo pain relief. Nature 2024; 632:1092–100. PMID: 39048016. Author: Steven P. Cohen, M.D. Anesthesiology December 2024, Vol. 141, A13–A15. The placebo effect exerts an enormous role for pain, being greater than the intrinsic effects of most therapies. Yet, the neural basis remains unclear. A 7-day placebo analgesia conditioning (PAC) assay was developed, […]
Read MoreAuthors: James M Hitt, M.D., Ph.D. et al Anesthesiology November 2024. Background Prescription rates for buprenorphine in opioid use disorder are increasing, and recent guidelines recommend its continuation during and after surgery; however, evidence from clinical outcome studies is limited. We tested the hypotheses that 1) perioperative continuation of buprenorphine does not result in higher […]
Read MoreAuthors: Annie Xin, PhD et al Anesthesiology November 2024. Background The GAS trial demonstrated evidence that most neurodevelopmental outcomes at 2 years and 5 years of age in infants who received a single general anaesthetic (GA) for elective inguinal herniorrhaphy were clinically equivalent when compared to infants who did not receive GA. More than 20% […]
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