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Excitement is mounting about a new class of drugs for migraine prevention. In one of the most recent developments, a new phase 2 trial of ALD403, a humanized monoclonal antibody directed against calcitonin gene-related peptide (CGRO) showed that the drug was safe and effective. Results also showed that adverse events associated with the drug were […]
Read MorePublished in Rheumatology International (Sep 2014) Authors: Bjersing J et al Fibromyalgia (FM) is characterized by generalized chronic pain and reduced pain thresholds. Disturbed neuroendocrine function and impairment of growth hormone/insulin-like growth factor-1 is common. However, the pathophysiology of FM is not clear. MicroRNAs are important regulatory factors reflecting interface of genes and environment. Our […]
Read MoreMemantine, a drug primarily used to treat patients with Parkinson’s disease and Alzheimer’s disease, reduced pain and improved quality of life in patients with fibromyalgia, according to a study published in Pain. “This is the first randomised, controlled study of memantine for the treatment of fibromyalgia,” write Bárbara Oliván-Blázquez, from the Department of Psychology and […]
Read MorePatients who receive epinephrine during resuscitation after cardiac arrest are less likely to survive with a good neurologic outcome, a study in the Journal of the American College of Cardiology suggests. Researchers analyzed data from more than 1500 patients who were successfully resuscitated after an out-of-hospital cardiac arrest and were subsequently treated at a large […]
Read MoreAuthors: Cohen SP et al., Anesthesiology 2014 Nov 121:1045 In a nonblinded, randomized trial, epidural steroid injections were not significantly better than conservative treatment. Data on epidural steroid injections for cervical radiculopathy are largely observational, and results of the few small randomized trials have been inconclusive. In this multicenter trial, U.S. investigators randomized 169 patients […]
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