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Published in Br J Anaesth. 2014;113(3):340-343. It is fascinating and alluring—the evidence is converging that with goal-directed haemodynamic therapy we can actively contribute to better postoperative outcomes of our patients, particularly in our high-risk patients. And this is potentially possible, as suggested by an overwhelming number of publications from recent years, with completely non-invasive advanced […]
Read MoreNeosaxitoxin, a novel site 1 sodium channel blocker, significantly prolonged sensory blockade when combined with bupivacaine, with or without epinephrine, in the first-in-human trial of this compound. The study, presented here at Anesthesiology 2014, was distinguished as the Best Clinical Abstract. “Neosaxitoxin prolonged local anesthesia, when given either alone or with bupivacaine or epinephrine, while […]
Read MorePublished in Anaesth Crit Care and Pain. 2014;14(4):147-152. Introduction The type of surgery performed on the spine encompasses operations for trauma, deformity, and myelopathy. The complexity of procedures is continuing to increase and older patients with significant co-morbidities are being offered ever more major procedures for which they would have previously not been considered. Increasing […]
Read MorePublished in J Bone Joint Surg Am 2015 Feb 4; 97:e18 Authors: Sharrock NE. In an observational study, most outcomes favored regional anesthesia. For patients undergoing total hip arthroplasty, some evidence suggests that perioperative outcomes are more favorable with regional anesthesia than with general anesthesia. To shed additional light on this issue, U.S. researchers accessed […]
Read MoreThe number of patients reporting moderate to severe pain two weeks after surgery has decreased by 24% in the last decade, a new study found. Researchers surveyed 441 patients before they were discharged from the hospital, and then at one, two and three weeks after surgery. Patients were asked to rate their pain intensity and […]
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