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Uncategorized Published - 5 February, 2015    By - Dr Clemens
Possible Pathogenic Mechanism of Propofol Infusion Syndrome Involves Coenzyme Q

Authors: Arnaud Vincent Vanlander, M.D. et al Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 343-352. doi:10.1097/ALN.0000000000000484 Background: Propofol is a short-acting intravenous anesthetic agent. In rare conditions, a life-threatening complication known as propofol infusion syndrome can occur. The pathophysiologic mechanism is still unknown. Some studies suggested that propofol acts as uncoupling […]

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Uncategorized Published - 5 February, 2015    By - Dr Clemens
Factors Associated with Improved Survival after Resection of Pancreatic Adenocarcinoma: A Multivariable Model

Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 317-324. doi:10.1097/ALN.0000000000000489 Authors: Tyler R. Call, M.D et al Background: Several retrospective studies suggest that perioperative care and anesthetic management for cancer resection may influence cancer recurrence or patient survival. Various intraoperative techniques such as paravertebral blocks, decreased opioid use, immunomodulation, and perioperative antiinflammatory […]

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Uncategorized Published - 5 February, 2015    By - Dr Clemens
Neurophysiological Correlates of Sevoflurane-induced Unconsciousness

Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 307-316. doi:10.1097/ALN.0000000000000482 Authors: Stefanie Blain-Moraes, Ph.D. et al Background: Recent studies of anesthetic-induced unconsciousness in humans have focused predominantly on the intravenous drug propofol and have identified anterior dominance of alpha rhythms and frontal phase–amplitude coupling patterns as neurophysiological markers. However, it is unclear […]

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Uncategorized Published - 5 February, 2015    By - Dr Clemens
Sodium Bicarbonate and Renal Function after Cardiac Surgery: A Prospectively Planned Individual Patient Meta-analysis

Published in The Journal of the American Society of Anesthesiologists 2 2015, Vol.122, 294-306. doi:10.1097/ALN.0000000000000547 Authors: Michael Bailey, Ph.D. et al Background: The effect of urinary alkalinization in cardiac surgery patients at risk of acute kidney injury (AKI) is controversial and trial findings conflicting. Accordingly, the authors performed a prospectively planned individual patient data meta-analysis of the […]

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Uncategorized Published - 4 February, 2015    By - Dr Clemens
Obama Budget Gets Mixed Reviews from Providers, Advocates

The budget proposal calls for a permanent repeal of Medicare’s widely reviled sustainable growth rate funding formula for physicians, but also calls for about $400 billion in cuts, mostly to Medicare and Medicaid, over the next decade. The reaction from healthcare providers to the Obama Administration’s $4 trillion 2016 budget proposal has been mixed, but […]

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