Published in Ann Emerg Med 2015 Jan 7 Authors: Schaffer JT et al. Intranasal lidocaine has shown promise as a migraine treatment, but a trial of bupivacaine for unselected headaches disappoints. Prior research has shown intranasal lidocaine to be an effective treatment for migraine (NEJM JW Emerg Med Aug 16 1996). Now, investigators report results […]
Read MorePublished in J Pediatr 2014 Dec 165:1230 Authors: Adelgais KM et al. Abdominal tenderness, more than abdominal pain, predicted intra-abdominal injury and need for acute intervention. To evaluate the accuracy of patient-reported abdominal pain and physician-assessed abdominal tenderness for predicting intra-abdominal injuries in children, investigators conducted a planned secondary analysis of patients <18 years of […]
Read MoreOpioids are frequently prescribed to reproductive-aged women in the U.S., raising concerns about fetal exposure in unrecognized or unintended pregnancies, an MMWR article finds. Opioid exposure during pregnancy is potentially associated with increased risks for neonatal abstinence syndrome and birth defects. CDC researchers examined two databases — one of Medicaid recipients and the other of […]
Read MorePublished in Anesthesiology 2015 Jan 122:29 Authors: Pinheiro de Almeida J et al. A hemoglobin level of 9 g/dL was superior to 7 g/dL as a trigger for transfusion. Randomized trials have shown favorable outcomes with a restrictive red-cell transfusion strategy — that is, not transfusing until hemoglobin levels are <7 g/dL in general critical-care […]
Read MoreFood and Drug Administration (US) AUDIENCE: Pharmacy, Case Manager ISSUE: Hospira announced a voluntary recall of ketorolac tromethamine injection, USP in the United States and Singapore due to potential particulate. The presence of particulate has been confirmed through a customer report of visible, floating particulate identified in glass fliptop vials. The particulate was identified as […]
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