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Published in Anesthesiology. 2015 Jan;122(1):140-9 Authors: Khodayari-Rostamabad A et al BACKGROUND: The authors investigated the effect of remifentanil administration on resting electroencephalography functional connectivity and its relationship to cognitive function and analgesia in healthy volunteers. METHODS: Twenty-one healthy male adult subjects were enrolled in this placebo-controlled double-blind cross-over study. For each subject, 2.5 min of multichannel […]
Read MoreChondroitin sulfate plus glucosamine is comparable to celecoxib in reducing pain in patients with knee osteoarthritis and is a safe alternative for patients with cardiovascular or gastrointestinal conditions who have contraindications to celecoxib. The findings were presented here at the 2014 Annual Scientific Meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP) […]
Read MorePublished in Paediatr Anaesth. 2014 Nov;24(11):1149-57 Authors: Olischar M et al BACKGROUND: Tramadol is used following neonatal cardiac and general surgery. However, its ability to opioid-spare or facilitate earlier extubation in postoperative neonates is unquantified. OBJECTIVE: This randomized placebo-controlled trial aimed to assess whether tramadol’s addition to standard analgesia resulted in earlier extubation or reduced analgesic/sedative […]
Read MorePublished in Acta Anaesthesiol Scand. 2015 Feb;59(2):265-7. Authors: Pedersen AB et al Green urine from propofol infusion is a benign and rare side effect. The discolouration appears when clearance of propofol exceeds hepatic elimination, and extrahepatic elimination of propofol occurs. This case report presents a 24-year-old male with grass green discolouration of urine based on propofol […]
Read MoreThe US Food and Drug Administration (FDA) has approved extended-release hydrocodone bitartrate (Hysingla ER), an opioid analgesic to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Hydrocodone bitartrate ER has properties that are expected to reduce, but not totally prevent, abuse of the drug […]
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