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Authors: Jiang, Xue et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005731 This large longitudinal cohort study investigated whether chronic widespread pain (CWP) contributes to cognitive decline and dementia, as well as potential underlying mechanisms involving brain structure and systemic inflammation. Using data from nearly 190,000 UK Biobank participants followed over 13 years, researchers examined self-reported […]
Read MoreAuthors: Calabrese, Alberto et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005633 This comprehensive narrative review examines the expanding role of renin–angiotensin system (RAS) modulation in critical care, focusing on both classical and alternative pathways. The authors explore how the dual RAS axes—one promoting vasoconstriction and inflammation, the other vasodilation and tissue protection—may be therapeutically targeted […]
Read MoreAuthor: Xue, Fu-Shan M.D. et al Anesthesiology October 21, 2025. | DOI: 10.1097/ALN.0000000000005703 This Letter to the Editor comments on Zhang et al.’s recent study evaluating pyridoxine as part of a multimodal strategy for preventing postoperative nausea and vomiting (PONV) following gynecologic laparoscopic surgery. The authors commend the findings but raise concerns about potential confounding factors and the […]
Read MoreAuthors: Hight, Darren et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005762 This letter to the editor exposes a long-standing technical flaw in Bispectral Index (BIS) monitors (Medtronic, Ireland) that directly affects calculation of the spectral edge frequency 95 (SEF95), a standard electroencephalographic (EEG) measure used to gauge anesthetic depth. The authors—building on prior reports of […]
Read MoreHardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]
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