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Aspirin before cardiac surgery significantly reduced postoperative permanent stroke and infectious endocarditis, a benefit that was not associated with increased risks for other potential adverse events. According to Vwaire J. Orhurhu, MPH, there is scant research in the effect of aspirin administration before cardiac surgery. He and his colleagues at Beth Israel Deaconess Medical Center […]
Read MoreAdding perineural dexamethasone as an adjunct to traditional brachial plexus block radically extends the duration of the block and improves postoperative pain outcomes, a meta-analysis has found. Additionally, no reports of persistent nerve injury were attributed to perineural dexamethasone administration in the nine trials comprising the analysis. “Our group has done quite a bit of […]
Read MoreAnesthesia & Analgesia: April 2015 Authors: Thonnerieux, Magalie MD et al BACKGROUND: Alveolar recruitment maneuvers (ARMs) are known to improve perioperative morbidity but can transiently impact cardiac output (CO). This reproducible hemodynamic perturbation creates a clinical opportunity to test multiple devices during acute changes in CO. The objective of this study was to evaluate the […]
Read MoreAnesthesia & Analgesia: July 2015 Volume 121 pages 159-164 Authors: Lavoie, Anne MD et al BACKGROUND: Prophylactic administration of oxytocin as a part of active management of the third stage of labor reduces the risk of postpartum hemorrhage. Prophylactic oxytocin is often administered as an infusion rather than a bolus. The aim of the current […]
Read MoreAnesthesia & Analgesia: July 2015 Volume 121 page 90-96 Authors: Borrat, Xavier MD et al BACKGROUND: The purpose of this study was to identify optimal target propofol and remifentanil concentrations to avoid a gag reflex in response to insertion of an upper gastrointestinal endoscope. METHODS: Patients presenting for endoscopy received target-controlled infusions (TCI) of both […]
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