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Uncategorized Published - 23 July, 2015    By - Dr Clemens
Effectiveness of transcranial direct current stimulation preceding cognitive behavioural management for chronic low back pain: sham controlled double blinded randomised controlled trial

BMJ. April 2015; 350: h1640. Authors: Kerstin Luedtke postdoctoral researcher, et al Objective To evaluate the effectiveness of transcranial direct current stimulation alone and in combination with cognitive behavioural management in patients with non-specific chronic low back pain. Design Double blind parallel group randomised controlled trial with six months’ follow-up conducted May 2011-March 2013. Participants, physiotherapists, assessors, and […]

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Uncategorized Published - 23 July, 2015    By - Dr Clemens
Safety of deep sedation in young children with sickle cell disease: a retrospective cohort study

J Pediatr 2015 May;166(5):1226-32 Authors: Belmont AP et al OBJECTIVE: To assess the rates and types of complications associated with deep sedation in children with sickle cell disease (SCD) and to explore potential risk factors. STUDY DESIGN: This was a retrospective cohort study of children with SCD and a comparison group of children without SCD who underwent […]

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Uncategorized Published - 23 July, 2015    By - Dr Clemens
Neurocognitive dysfunction risk alleviation with the use of dexmedetomidine in perioperative conditions or as ICU sedation: a meta-analysis

Medicine (Baltimore) 2015 Apr;94(14):e597 Authors: Li B et al Abstract Many studies have reported the beneficial effects of dexmedetomidine on postoperative neurocognitive function but overall evidence is not as clear. We examined this conundrum by meta-analyzing studies that used dexmedetomidine in perioperative conditions or as intensive care unit (ICU) sedation and utilized reliable neurocognitive assessment tests. The […]

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Uncategorized Published - 23 July, 2015    By - Dr Clemens
FDA OKs First Patient-Controlled Patch for Postop Pain

The US Food and Drug Administration has approved fentanyl iontophoretic transdermal system (Ionsys, The Medicines Co), the first needle-free, patient-controlled, preprogrammed fentanyl delivery system for management of acute postoperative pain in adults requiring opioid analgesia in the hospital, according to a company news release. Ionsys is a “novel alternative” to traditional intravenous patient-controlled analgesia that uses […]

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Uncategorized Published - 22 July, 2015    By - Dr Clemens
Comparison of the efficacy and safety of sedation between dexmedetomidine-remifentanil and propofol-remifentanil during endoscopic submucosal dissection

World J Gastroenterol 2015 Mar 28;21(12):3671-8. Authors: Kim N et al AIM: To compare the efficacy and safety of sedation protocols for endoscopic submucosal dissection (ESD) between dexmedetomidine-remifentanil and propofol-remifentanil. METHODS: Fifty-nine patients scheduled for ESD were randomly allocated into a dexmedetomidine-remifentanil (DR) group or a propofol-remifentanil (PR) group. To control patient anxiety, dexmedetomidine or propofol was […]

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