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Uncategorized Published - 6 August, 2015    By - Dr Clemens
Analgesics Linked to Increased Homicide Risk

Psychotropic medications, including antidepressants, benzodiazepines, and particularly opiate and nonopiate analgesics, are associated with a significantly increased risk for homicide, new research shows. Jari Tiihonen, MD, PhD, professor, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden, and colleagues found that antidepressants increase the homicide risk by 31% and that benzodiazepines increase the risk by 45%. […]

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Uncategorized Published - 6 August, 2015    By - Dr Clemens
Dexmedetomidine Versus Remifentanil in Postoperative Pain Control After Spinal Surgery A Randomized Controlled Study

BMC Anesthesiol. 2015;15(21) Authors: Wonjung Hwang et al Background Total intravenous anesthesia (TIVA) is used widely in spinal surgery because inhalational anesthetics are known to decrease the amplitude of motor evoked potentials. Presently, dexmedetomidine is used as an adjuvant for propofol-based TIVA. We compared the effects of remifentanil and dexmedetomidine on pain intensity as well […]

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Uncategorized Published - 6 August, 2015    By - Dr Clemens
Pregabalin Improves Fibromyalgia-Related Sleep Disturbance

Clin J Pain. 2015 May 28 Authors: Roth T1 et al OBJECTIVE: To investigate the effect of pregabalin on wake and sleep bout parameters. METHODS: A post hoc analysis of polysomnography data from a randomized, placebo-controlled, crossover study investigating the effect of pregabalin (150-450 mg/d) and placebo on sleep in fibromyalgia (FM). Eligible patients had […]

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Uncategorized Published - 6 August, 2015    By - Dr Clemens
Safety and Efficacy of Needle-Free Powder Lidocaine Delivery System in Adult Patients Undergoing Venipuncture or Peripheral Venous Cannulation: Randomized, Double-blind, Placebo-controlled Trial

Clin J Pain. 2015 May 15 Authors: Zempsky WT1 et al OBJECTIVES: The purpose of this study was to evaluate the efficacy, safety, and tolerability of a needle-free powder lidocaine delivery system compared with sham placebo in adults. METHODS: Adult subjects participated in this multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Subjects were randomly allocated to […]

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Uncategorized Published - 5 August, 2015    By - Dr Clemens
Association of Intraoperative Hypotension with Acute Kidney Injury after Elective Noncardiac Surgery

Anesthesiology published on 7 2015 Authors: Louise Y. Sun, M.D. et al      . Background: Intraoperative hypotension (IOH) may be associated with postoperative acute kidney injury (AKI), but the duration of hypotension for triggering harm is unclear. The authors investigated the association between varying periods of IOH with mean arterial pressure (MAP) less than 55, less than 60, […]

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