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Uncategorized Published - 10 September, 2015    By - Dr Clemens
The RECITE Study: A Canadian Prospective, Multicenter Study of the Incidence and Severity of Residual Neuromuscular Blockade

Anesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 366–372 Authors: Fortier, Louis-Philippe MSc, MD, FRCPC et al BACKGROUND: Postoperative residual neuromuscular blockade (NMB), defined as a train-of-four (TOF) ratio of <0.9, is an established risk factor for critical postoperative respiratory events and increased morbidity. At present, little is known about […]

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Uncategorized Published - 10 September, 2015    By - Dr Clemens
Rationale and Design of the Balanced Anesthesia Study: A Prospective Randomized Clinical Trial of Two Levels of Anesthetic Depth on Patient Outcome After Major Surgery

Anesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 357–365 Authors: Short, Timothy G. MBChB, MD, FANZCA et al BACKGROUND: An association between relatively deep anesthesia, as guided by the bispectral index (BIS), and increased postoperative mortality has been demonstrated in 6 of 8 published observational studies, but association does not […]

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Uncategorized Published - 10 September, 2015    By - Dr Clemens
Reversal of Pipecuronium-Induced Moderate Neuromuscular Block with Sugammadex in the Presence of a Sevoflurane Anesthetic: A Randomized Trial

Anesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 373–380 Authors: Tassonyi, Edömér MD, PhD, DSc et al BACKGROUND: Pipecuronium is a steroidal neuromuscular blocking agent. Sugammadex, a relaxant binding γ-cyclodextrin derivative, reverses the effect of rocuronium, vecuronium, and pancuronium. We investigated whether sugammadex reverses moderate pipecuronium-induced neuromuscular blockade (NMB) and […]

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Uncategorized Published - 10 September, 2015    By - Dr Clemens
Lung Injury After One-Lung Ventilation: A Review of the Pathophysiologic Mechanisms Affecting the Ventilated and the Collapsed Lung

Anesthesia & Analgesia: August 2015-Volume 121-Issue 2-page 302-318 Authors: Lohser, Jens MD et al Lung injury is the leading cause of death after thoracic surgery. Initially recognized after pneumonectomy, it has since been described after any period of 1-lung ventilation (OLV), even in the absence of lung resection. Overhydration and high tidal volumes were thought […]

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Uncategorized Published - 9 September, 2015    By - Dr Clemens
High-Pressure Oxygen Can Effectively Treat Fibromyalgia

A study published in PLoS ONE has found that women with fibromyalgia were able to drastically reduce, or even eliminate, their use of pain medication following hyperbaric oxygen treatment. The study authors believe they have also identified the primary factor causing fibromyalgia: the disruption of the brain mechanism for processing pain. “As a physician, the […]

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