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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Intranasal midazolam during presurgical epilepsy monitoring is well tolerated, delays seizure recurrence, and protects from generalized tonic-clonic seizures

Epilepsia. 2015 Sep;56(9):1408-14 AUTHORS: Kay L et al OBJECTIVE: To evaluate the tolerability and efficacy of the ictal and immediate postictal application of intranasal midazolam (in-MDZ) in adolescents and adults during video-electroencephalography (EEG) monitoring. METHODS: Medical records of all patients treated with in-MDZ between 2008 and 2014 were reviewed retrospectively. For each single patient, the time […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Urethrocutaneous fistula following hypospadias repair: regional anesthesia and other factors

Paediatr Anaesth. 2015 Jul AUTHORS; Zaidi RH et al BACKGROUND: Urethrocutaneous fistula is a well-known complication of hypospadias surgery. A recent prospective study by Kundra et al. (Pediatr Anesth 2012) has suggested that caudal anesthesia may increase the risk of fistula formation. We sought to evaluate this possible association and determine if any other novel factors may […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Propofol Regulates the Surface Expression of GABAA Receptors: Implications in Synaptic Inhibition

Anesthesia & Analgesia: August 2015 AUTHORS: Li, Yuwen PhD et al BACKGROUND: The anesthetic propofol is thought to induce rapid hypnotic sedation by potentiating [gamma]-aminobutyric acid receptor (GABAAR) activity. Little is known about the molecular mechanisms of propofol in modulating inhibitory synaptic transmission. We aimed to investigate the role of propofol in modulating surface expression […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Is That Hospital Stay Setting Up Your Patients for Sepsis?

A new study suggests that a routine hospital stay can disturb the balance of the microbiome so much that it sets up some older individuals for life-threatening sepsis. Researchers found that older adults are three times more likely to develop sepsis, a systemic catastrophic response to infection, in the first three months after leaving a […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
A comparison of the postoperative pain experience in children with and without attention-deficit hyperactivity disorder (ADHD)

Paediatr Anaesth 2015 Oct;25(10):1020-5 AUTHORS: Rosandwr S  et al BACKGROUND: Children with attention-deficit hyperactivity disorder (ADHD) may experience pain differently compared to other children, yet the evidence is equivocal regarding whether pain is heightened or dampened. This prospective observational study, therefore, was designed to compare the postoperative pain experiences in children with and without ADHD. METHODS: Children […]

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