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Uncategorized Published - 19 June, 2015    By - Dr Clemens
Intravenous ketamine during spinal and general anaesthesia for caesarean section: systematic review and meta-analysis

Published in Acta Anaestesiol Scand 2015 Apr;59(4):414-26 Authors: Heesen M et al BACKGROUND: Intravenous ketamine has been used during general and regional anaesthesia for caesarean section. No systematic review and meta-analysis on the desired effects and adverse effects of ketamine administration during caesarean section have yet been performed. METHODS: After a systematic literature search a meta-analysis was […]

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Uncategorized Published - 19 June, 2015    By - Dr Clemens
Transversus abdominis plane block vs. wound infiltration in Caesarean section: a randomised controlled trial

Published in Acta Anaesthesiol Scand. 2015 Apr;59(4):496-504 Authors: Telnes A et al BACKGROUND: Multiple studies suggest that transversus abdominis plane (TAP) block (without intrathecal morphine) after Caesarean section (CS) reduces post-operative morphine consumption. In our study, we wanted to compare the analgesic effect of TAP block with infiltration of the wound after CS. METHODS: We included […]

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Uncategorized Published - 19 June, 2015    By - Dr Clemens
Keys to Treating Sepsis Are Early Recognition, Fluids, and Antibiotics

Authors: Mouncey PR et al., N Engl J Med 2015 Apr 2; 372:1301 A third trial shows no benefit for early goal-directed therapy for septic shock. In 2001, a single-center randomized trial demonstrated a significant mortality benefit for early goal-directed therapy (EGDT) in patients with septic shock (NEJM JW Gen Med Dec 15 2001 and N Engl J Med 2001; […]

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Uncategorized Published - 18 June, 2015    By - Dr Clemens
Complexities of Opioid-Induced Hyperalgesia Poorly Understood

Opioid-induced hyperalgesia is among the most pressing concerns in the national discussion of opioid addiction, underscored by the US Food and Drug Administration’s (FDA) call for clinical trials to better understand the risks, but the issue is mired in more complexities and confusion than many may even realize, an expert says. Norman Harden, MD, from […]

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Uncategorized Published - 18 June, 2015    By - Dr Clemens
Tissue Oxygenation as a Target for Goal-directed Therapy in High-risk Surgery A Pilot Study

Authors: Paul A van Beest et al BMC Anesthesiol. 2014;14(122) Background Tissue hypoperfusion occurs frequently during surgery and may contribute to postoperative organ dysfunction. There is a need for perioperative treatment protocols aiming at improving tissue oxygenation (StO2). We hypothesised that intra-operative optimisation of StO2 improves tissue perfusion and thus reduces postoperative complications. Furthermore, we evaluated the feasibility […]

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