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Uncategorized Published - 23 June, 2015    By - Dr Clemens
Hyperinsulinemic Normoglycemia Does Not Meaningfully Improve Myocardial Performance during Cardiac Surgery: A Randomized Trial

Published in Anesthesiology 6/2015 Authors: Andra E. Duncan, MD Background: Glucose–insulin–potassium (GIK) administration during cardiac surgery inconsistently improves myocardial function, perhaps because hyperglycemia negates the beneficial effects of GIK. The hyperinsulinemic normoglycemic clamp (HNC) technique may better enhance the myocardial benefits of GIK. The authors extended previous GIK investigations by (1) targeting normoglycemia while administering a GIK […]

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Uncategorized Published - 23 June, 2015    By - Dr Clemens
Association between Withholding Angiotensin Receptor Blockers in the Early Postoperative Period and 30-day Mortality: A Cohort Study of the Veterans Affairs Healthcare System

Published in Anesthesiology 5 2015 Authors: Susan M. Lee MD FRCPC et al Background: Despite widespread use, there is limited information to guide perioperative management of angiotensin receptor blockers (ARBs). Methods: In this retrospective cohort study, the authors evaluated the patterns of postoperative ARB use in veterans regularly prescribed ARBs admitted for noncardiac surgery at the Veterans Affairs […]

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Uncategorized Published - 23 June, 2015    By - Dr Clemens
Shift From IV to Oral Sedation for Pain Procedures?

The transition from extensive use of intravenous (IV) sedation for interventional pain procedures to almost exclusive use of oral anxiolysis at an outpatient pain center led to significant improvements in patient satisfaction and recovery times, a new study shows. But not all practitioners are on board with such a policy, citing potential safety issues. “The […]

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Uncategorized Published - 22 June, 2015    By - Dr Clemens
Preanesthesia Sedative Unnecessary, RCT Data Suggest

It may be time to rethink the widespread practice of routinely giving a sedative before anesthesia to patients undergoing elective surgery, suggest findings of the randomized multicenter PremedX trial. Results published in the March 3 issue of JAMA show that compared with no premedication or a placebo, lorazepam premedication failed to improve patients’ overall satisfaction with the perioperative […]

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Uncategorized Published - 22 June, 2015    By - Dr Clemens
Dexmedetomidine-ketamine combination and caudal block for superficial lower abdominal and genital surgery in children

Published in Paediatr Anaeth 2015 May; 25 Authors: Ibacache ME et al BACKGROUND: The use of dexmedetomidine-ketamine combination to perform different diagnostic and surgical pediatric procedures has increased. The optimal ketamine dose to combine with dexmedetomidine has not been determined. The goal of this study was to determine the ED50 and ED95 of ketamine, which in […]

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