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High opioid exposure is a prognostic factor for shorter overall survival, according to a study presented here at the 2015 American Society of Clinical Oncology (ASCO) Palliative Care in Oncology Symposium. The study involved patients with stage IV non-hematologic malignancies. For these and other patients with advanced cancer, pain is a challenging problem. “Opioids are […]
Read MoreInt Orthop 2015 Sep 15. Authors: Sanel S et al AIM: There are many alternatives for post-operative pain relief in patients who have had general anaesthesia. The aim of this study was to evaluate the efficacy of intra-articular bupivacaine + morphine and bupivacaine + tenoxicam applications in post-operative pain control in patients undergoing knee arthroscopy with general […]
Read MoreClin Ther 2015 Nov 1;37(11):2420-38. Authors: Buynak R et al PURPOSE: Tapentadol extended release (ER) has demonstrated efficacy and safety for the management of moderate to severe, chronic pain in adults. This study evaluated the long-term safety and tolerability of tapentadol ER in patients with chronic osteoarthritis or low back pain. METHODS: Patients were enrolled in this […]
Read MoreMost patients who experience a nonfatal prescription opioid overdose continue to receive opioids afterward, increasing their risk for a second overdose, finds a retrospective study in the Annals of Internal Medicine. Using data from a U.S. health insurer, researchers studied some 2800 adults who survived a first opioid overdose during long-term opioid therapy for noncancer pain. […]
Read MoreAn online calculator that assesses patient-specific risk and guides surgical decision making changes the perceptions that surgeons have about operative risk, but not their decisions to recommend surgery, according to a randomized controlled trial. The surgical risk calculator developed by the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP), has a “high degree […]
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