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Published in Paediatr Anaesth, 2015 May Authors: Chidambaran V et al BACKGROUND: Optimal dosing of propofol to maintain appropriate anesthetic depth is challenging in severely obese (SO) adolescents. We previously reported that total body weight (TBW) is predictive of propofol clearance. This study was aimed at characterizing pharmacokinetics (PK) and pharmacodynamics (PD) of propofol in SO […]
Read MoreAuthors: Goldberg H et al. JAMA 2015 May 19. And treatment offered no relief from pain. Oral steroids are used commonly in patients with acute lumbar radiculopathy or sciatica, but strong evidence of benefit is lacking. In this study, researchers at a large California health system randomized 269 patients (mean age, 46) with acute sciatica, magnetic resonance […]
Read MoreThe table below shows the top 100 diagnosis-related groups in the United States in 2013 based on total inpatient discharges. The Centers for Medicare and Medicaid services released the data Monday as part of a push to make the costs for these treatments more transparent. The data only includes treatments billed in a fee-for-service model […]
Read MorePerioperative β-blockade was associated with lower 30-day mortality in patients with three to four cardiac risk factors undergoing noncardiac surgery (NCS), but with increased mortality in patients with no cardiac risk factors, according to a retrospective cohort study published in May JAMA Surgery. “Perioperative β-blockade is widely accepted in patients who undergo cardiac surgery,” write Mark […]
Read MorePhysicians must become better prepared to answer patients’ questions about cannabis because its use in medicine is exploding, according to a leading researcher. “It’s high time we got up to speed with the language and the issues around communication on this,” said Mark Ware, MBBS, MSc, from McGill University Health Centre in Montreal, Quebec, Canada. […]
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