⭐ Recognized by FeedSpot: #12 Best Anesthesiology Blog Worldwide

Uncategorized Published - 18 December, 2015    By - Dr Clemens
Very Low Frequency Deep-Brain Stimulation Improves Neuropathic Pain After Spinal-Cord Injury

Very low frequency (<2 Hz) stimulation may be more effective at controlling neuropathic pain in patients with spinal-cord injury than higher frequencies (>10 Hz), according to a small, 2-subject study presented on September 28 at the 140th Annual Meeting of the American Neurological Association (ANA). Corneliu Luca MD, PhD, University of Miami Health System, Miami, […]

Read More
Uncategorized Published - 17 December, 2015    By - Dr Clemens
Glial Attenuation With Ibudilast in the Treatment of Medication Overuse Headache: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial of Efficacy and Safety

Headache, 2015 Oct;55(9):1192-208. Authors: Johnson JL et al BACKGROUND: Medication overuse headache (MOH) is a condition bordering between a chronic pain condition and a substance dependence disorder. Activation of immunocompetent glial cells in the central nervous system has been linked to both pathological pain and drug addiction/reward. Preclinically, ibudilast attenuates glial activation and is able to reduce […]

Read More
Uncategorized Published - 17 December, 2015    By - Dr Clemens
Does Extended-Release Liposomal Bupivacaine Better Control Pain Than Bupivacaine After Total Knee Arthroplasty (TKA)? A Prospective, Randomized Clinical Trial.

J Arthroplasty, 2015 Sep;30 Authors: Schroer WC et al Liposomal bupivacaine periarticular injection (PAI) offers sustained bupivacaine release after TKA, but few prospective independent studies exist. In this prospective, blinded study, liposomal bupivacaine was randomized against bupivacaine and incorporated into a comprehensive multimodal pain management protocol. 111 primary TKAs were randomized to receive PAI: 58 patients received […]

Read More
Uncategorized Published - 17 December, 2015    By - Dr Clemens
Beta-Blockade and Other Perioperative Pharmacological Protectors

 What Is Now Available and Efficacious? Authors: J. W. Sear et al Br J Anaesth. 2015;115(3):333-336. Publication, in 2008, of the results of POISE, the largest randomized controlled trial (RCT) of perioperative beta-blockade, confirmed previous studies that had shown beta-blockade to offer cardiac protection in patients with, or at risk for, coronary heart disease.[1] However, this protection […]

Read More
Uncategorized Published - 17 December, 2015    By - Dr Clemens
Using Clinical Parameters to Guide Fluid Therapy in High-Risk Thoracic Surgery

A Retrospective, Observational Study Authors: Lars Stryhn Bjerregaard et BMC Anesthesiol. 2015;15(91) Background: Despite extensive research, the debate continues as to the optimal way of guiding intraoperative and postoperative fluid therapy. In 2009 we changed our institutional guideline for perioperative fluid therapy in patients undergoing extrapleural pneumonectomy (EPP) and implemented the use of central venous oxygen saturation […]

Read More