Authors: Jean Guglielminotti MD PhD et al Anesthesiology 11 2015, Vol.123, 1013-1023 Background: Cesarean delivery (CD) is associated with significantly increased risks of anesthesia-related adverse events (ARAEs) and nonanesthetic perioperative morbidity compared with vaginal delivery. Temporal trends in these adverse outcomes remain unknown despite efforts to improve maternal safety. This study examines temporal trends in ARAEs and […]
Read MoreBoth acupuncture and the Alexander Technique can improve chronic neck pain, according to a study in the Annals of Internal Medicine. Over 500 U.K. patients with nonspecific neck pain of at least 3 months’ duration were randomized to one of three strategies: 12 acupuncture sessions plus usual care, 20 one-to-one Alexander Technique lessons plus usual care, […]
Read MoreAuthors: Hendriksen JMT et al., BMJ 2015 Sep 8; 351:h4438 In the primary care setting, Wells and Geneva rules all performed well. How accurate are prediction rules, combined with point-of-care D-dimer testing, for ruling out pulmonary embolism (PE) in the primary care setting? In a systematic review followed by a validation study, researchers assessed five rules and specific […]
Read MoreAuthors: Wechsler ME et al., JAMA 2015 Oct 27; 314:1720 Tiotropium is not inferior to long-acting β-agonists for add-on asthma therapy. National asthma guidelines recommend long-acting β-agonists (LABAs) for patients whose asthma is not controlled by low-dose inhaled corticosteroids (ICS; J Allergy Clin Immunol 2007; 120:5 Suppl:S94); however, LABAs might be associated with risk for severe asthma exacerbations. […]
Read MoreAuthors: Gill JC et al., Blood 2015 Oct 22; 126:2038 Outcomes were excellent in 96.9% of bleeds in patients with severe disease. Patients with severe von Willebrand disease (VWD) have persistent, recurrent episodes of mucosal bleeding, menorrhagia, and bleeding with surgery or trauma. Treatment with plasma-derived von Willebrand factor (VWF) concentrates controls bleeding but exposes patients to […]
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