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Clin Ther. 2015 Nov 1;37(11):2468-75. Authors: Bista SR et al PURPOSE: Fentanyl is widely used to relieve cancer pain. However there is great interpatient variation in the dose required to relieve pain and little knowledge about the pharmacokinetic and pharmacodynamic (PK/PD) relationship of fentanyl and pain control. Patients with cancer are fragile and there is reluctance on […]
Read MoreAnesthesia & Analgesia: September 2015 Authors: Castro-Alves, Lucas J. MD et al BACKGROUND: Postsurgical quality of recovery is worse in female than that in male patients. Duloxetine has been used successfully for the treatment of chronic pain conditions, but its use for preventing acute postoperative pain has been limited to a single previous study. More […]
Read MoreAnesthesia & Analgesia: September 2015 Authors: Ahn, Hyun Joo MD, PhD et BACKGROUND: Fluid is restricted in thoracic surgery to reduce acute lung injury, and hydroxyethyl starches (HES) are often administered to reduce fluid amount. This strategy may contribute to the development of acute kidney injury (AKI). We evaluated the incidence, risk factors, and prognosis […]
Read MoreAnesthesia & Analgesia: September 2015 Authors: Fritz, Bradley A. MD et al BACKGROUND: Postoperative delirium is a common complication associated with increased morbidity and mortality, longer hospital stays, and greater health care expenditures. Intraoperative electroencephalogram (EEG) slowing has been associated previously with postoperative delirium, but the relationship between intraoperative EEG suppression and postoperative delirium has […]
Read MoreIdentifying a child presenting with a difficult airway may not be quite as easy as pediatric anesthesiologists believe, according to a chart review by a Canadian research team. Investigators at The Hospital for Sick Children, in Toronto, found that nearly 20% of difficult airways were unanticipated and more than half occurred in patients with no […]
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