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Crit Care, 2015 Sep 23;19(1):295. Authors: Pluims WA et al Endotracheal intubation is frequently complicated by laryngeal edema, which may present as postextubation stridor or respiratory difficulty or both. Ultimately, postextubation laryngeal edema may result in respiratory failure with subsequent reintubation. Risk factors for postextubation laryngeal edema include female gender, large tube size, and prolonged intubation. Although […]
Read MoreMedications play an important role in managing patients with opioid use disorders, but there are not enough physicians with the knowledge and ability to use these often-complex treatments. New evidence-based recommendations on the use of prescription medications for the treatment of opioid addiction are published in the October/November issue of the Journal of Addiction Medicine, the […]
Read MorePainful diabetic peripheral neuropathy (DPN) can be effectively treated with hepatocyte growth factor gene therapy, according to results of a phase 2 clinical trial presented at the 140th Annual Meeting of the American Neurological Association (ANA). “Diabetic peripheral neuropathy can cause debilitating pain with no effective treatment, and hepatocyte growth factor has potent neurotropic and […]
Read MoreVery low frequency (<2 Hz) stimulation may be more effective at controlling neuropathic pain in patients with spinal-cord injury than higher frequencies (>10 Hz), according to a small, 2-subject study presented on September 28 at the 140th Annual Meeting of the American Neurological Association (ANA). Corneliu Luca MD, PhD, University of Miami Health System, Miami, […]
Read MoreHeadache, 2015 Oct;55(9):1192-208. Authors: Johnson JL et al BACKGROUND: Medication overuse headache (MOH) is a condition bordering between a chronic pain condition and a substance dependence disorder. Activation of immunocompetent glial cells in the central nervous system has been linked to both pathological pain and drug addiction/reward. Preclinically, ibudilast attenuates glial activation and is able to reduce […]
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