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Khandelwal N et al., Anesth Analg 2016 Feb 10; In this retrospective study, patients intubated in a semi-erect, head-forward position had lower rates of peri-intubation adverse events than those in a supine position. Desaturation and poor direct laryngeal views are two important factors leading to intubation failure. In the operating room (OR), direct laryngoscopy is easier when […]
Read MoreEdited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Diclofenac, etoricoxib, and rofecoxib were associated with the greatest pain reduction for patients with knee or hip osteoarthritis, while acetaminophen was not superior to placebo, in a network meta-analysis in the Lancet. (Etoricoxib is not available in the U.S.; rofecoxib was withdrawn worldwide in 2004.) Researchers assessed […]
Read Moreby Erica L. Holland, MD; Carli D. Hoaglan, MD; Martha A. Carlstead, CRNA; Ryan P. Beecher, CRNA; Grete H. Porteous, MD Introduction Loss of electrical power in a hospital is a patient safety hazard that has been neglected in medical training and research.1,2 The technology-rich environment of the operating room (OR) puts patients at risk should […]
Read Moreby Karl E. Hammermeister, MD; Michael Bronsert, PhD; Joshua S. Richman, MD, PhD; and William G. Henderson, PhD Historical The earliest description of curare, a naturally occurring predecessor of the neuromuscular blocking agents commonly used today in anesthesia, has been attributed to Sir Walter Raleigh in his 1596 book, The Discoverie of the Large, Rich, and […]
Read Moreby Glenn Murphy, MD The Neuromuscular Research Group at Organon Newhouse Scotland (east of Glasgow) had been working on the development of fast-onset, short-acting, nondepolarizing steroidal neuromuscular blocking agents since the 1960s, which led to the development of pancuronium, vecuronium and rocuronium. Shortly after the launch of rocuronium, questions arose about a possible action of […]
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