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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Urethrocutaneous fistula following hypospadias repair: regional anesthesia and other factors

Paediatr Anaesth. 2015 Jul AUTHORS; Zaidi RH et al BACKGROUND: Urethrocutaneous fistula is a well-known complication of hypospadias surgery. A recent prospective study by Kundra et al. (Pediatr Anesth 2012) has suggested that caudal anesthesia may increase the risk of fistula formation. We sought to evaluate this possible association and determine if any other novel factors may […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Propofol Regulates the Surface Expression of GABAA Receptors: Implications in Synaptic Inhibition

Anesthesia & Analgesia: August 2015 AUTHORS: Li, Yuwen PhD et al BACKGROUND: The anesthetic propofol is thought to induce rapid hypnotic sedation by potentiating [gamma]-aminobutyric acid receptor (GABAAR) activity. Little is known about the molecular mechanisms of propofol in modulating inhibitory synaptic transmission. We aimed to investigate the role of propofol in modulating surface expression […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Is That Hospital Stay Setting Up Your Patients for Sepsis?

A new study suggests that a routine hospital stay can disturb the balance of the microbiome so much that it sets up some older individuals for life-threatening sepsis. Researchers found that older adults are three times more likely to develop sepsis, a systemic catastrophic response to infection, in the first three months after leaving a […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
A comparison of the postoperative pain experience in children with and without attention-deficit hyperactivity disorder (ADHD)

Paediatr Anaesth 2015 Oct;25(10):1020-5 AUTHORS: Rosandwr S  et al BACKGROUND: Children with attention-deficit hyperactivity disorder (ADHD) may experience pain differently compared to other children, yet the evidence is equivocal regarding whether pain is heightened or dampened. This prospective observational study, therefore, was designed to compare the postoperative pain experiences in children with and without ADHD. METHODS: Children […]

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Uncategorized Published - 28 September, 2015    By - Dr Clemens
Preparing Parents to Be Present for Their Child’s Anesthesia Induction: A Randomized Controlled Trial

Anesthesia & Analgesia: October 2015 – Volume 121 – Issue 4 – p 1001–1010 AUTHORS: Bailey, Kristen M. MSc et al BACKGROUND: The purpose of this study is to compare the effectiveness of a brief preparation intervention for parental presence during induction of anesthesia (PPIA preparation) with a PPIA with standard preparation (PPIA standard). METHODS: […]

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