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Uncategorized Published - 9 March, 2016    By - Dr Clemens
The Feasibility of a Completely Automated Total IV Anesthesia Drug Delivery System for Cardiac Surgery.

Anesthesia & Analgesia: January 2016 AUTHORS: Zaouter, Cedrick MD et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 components of general anesthesia: hypnosis, analgesia, and muscle relaxation. METHODS: […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Anesthesia and Cognitive Decline: No Link?

There is no significant link between exposure to general anesthesia and the development of mild cognitive impairment (MCI) in individuals aged 40 years and older, a large, comprehensive, population-based study shows. The potential link between exposure to surgical anesthesia, MCI, and dementia has been a matter of recent debate, with previous research contradicting the current […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children.

Am J Respir Crit Care Med. 2016 Jan 21 AUTHORS: Vet NJ et al RATIONALE: Various in vitro, animal and limited human adult studies suggest a profound inhibitory effect of inflammation and disease on Cytochrome P450 3A (CYP3A)-mediated drug metabolism. Studies showing this relationship in critically ill patients are lacking, while clearance of many CYP3A drug […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Electrical Stimulation of the Trigeminal Ganglion and Intrathecal Drug Delivery Systems for the Management of Corneal Neuropathic Pain

Cornea. 2016 Apr;35(4):576-7. AUTHORS: Sayegh RR et al PURPOSE: This case study reports on 2 novel neuromodulatory approaches in the management of a particularly recalcitrant case of corneal neuropathic pain. METHODS: Report of a case RESULTS: : A 32-year-old woman presented with intractable bilateral dry eye-like symptoms and corneal neuropathic pain after undergoing laser in situ […]

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Uncategorized Published - 8 March, 2016    By - Dr Clemens
Gradient between dorsalis pedis and radial arterial blood pressures during sevoflurane anaesthesia: A self-control study in patients undergoing neurosurgery

Eur J Anaesthesiol. 2016 Feb;33(2):110-7 AUTHORS: Chen Y et al BACKGROUND: The dorsalis pedis artery (DPA) is a good alternative to the radial artery (RA) for invasive blood pressure monitoring when the upper limb is burned or injured, or if the RA is not available. Understanding the pattern of pressure difference between DPA and the commonly […]

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