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Anesthesiology 4 2016, Vol.124, 878-884. Authors: Liping Han, M.D., M.Sc. et al Background: Propofol (2,6-diisopropylphenol) is one of the most frequently used anesthetic agents. One of the main side effects of propofol is to reduce blood pressure, which is thought to occur by inhibiting the release of catecholamines from sympathetic neurons. Here, the authors hypothesized that propofol-induced […]
Read MoreAnesthesiology 4 2016, Vol.124, 785-794. Authors: Derryn A. Gargiulo, M.Pharm.Clin., Reg.Pharm.N.Z. et al Background: The aseptic techniques of anesthesiologists in the preparation and administration of injected medications have not been extensively investigated, but emerging data demonstrate that inadvertent lapses in aseptic technique may be an important contributor to surgical site and other postoperative infections. Methods: A prospective, […]
Read MoreAnesthesiology 4 2016, Vol.124, 837-845. Authors: Karim S. Ladha, M.D., M.Sc. et al Background: Practice guidelines for perioperative pain management recommend that multimodal analgesic therapy should be used for all postsurgical patients. However, the proportion of patients who actually receive this evidence-based approach is unknown. The objective of this study was to describe hospital-level patterns in […]
Read MoreAuthor: Laszlo Vutskits, M.D., Ph.D. Anesthesiology 4 2016, Vol.124, 758-760. ADVERSE experiences during the perinatal period are associated with altered pain sensitivity and long-term behavioral sequels, including significant emotional problems during childhood and major psychotic episodes, anxiety, depression, and suicides in adolescence or adulthood.1 Exposure to painful stimuli is one major cause of these harmful incidents, especially […]
Read MoreAuthors: Allan F. Simpao, M.D., M.B.I.; Jorge A. Gálvez, M.D. Anesthesiology 4 2016, Vol.124, 750-751. THE pulse oximeter has become a virtually indispensable monitor for measuring a patient’s peripheral capillary oxygen saturation (Spo2) accurately and reliably in a continuous, noninvasive fashion.1 Despite its ubiquitous use as a detector of hypoxemia, pulse oximetry has limited utility to herald an […]
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