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Uncategorized Published - 20 September, 2016    By - Dr Clemens
The Association Between Progesterone, Estradiol, and Oxytocin and Heat Pain Measures in Pregnancy: An Observational Cohort Study

Anesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 396–401 AUTHORS: Frölich, Michael A. MD et al BACKGROUND: Hormonal action has been implicated as a possible mechanism for pregnancy-induced analgesia. Previous investigators have reported an increase in heat pain tolerance during labor compared with nonpregnant controls and postulated it was because […]

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Uncategorized Published - 20 September, 2016    By - Dr Clemens
The Effect of Early Goal-Directed Therapy on Outcome in Adult Severe Sepsis and Septic Shock Patients: A Meta-Analysis of Randomized Clinical Trials

Anesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 371–381 AUTHORS: Xu, Jing-Yuan MD et al BACKGROUND: Whether early goal-directed therapy (EGDT) improves outcome in severe sepsis and septic shock remains unclear. We performed a meta-analysis of existing clinical trials to examine whether EGDT improved outcome in the resuscitation of adult […]

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Uncategorized Published - 20 September, 2016    By - Dr Clemens
Ventilation-Induced Modulation of Pulse Oximeter Waveforms: A Method for the Assessment of Early Changes in Intravascular Volume During Spinal Fusion Surgery in Pediatric Patients

Anesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 346–356 AUTHORS: Alian, Aymen A. MD et al BACKGROUND: Scoliosis surgery is often associated with substantial blood loss, requiring fluid resuscitation and blood transfusions. In adults, dynamic preload indices have been shown to be more reliable for guiding fluid resuscitation, but these […]

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Uncategorized Published - 20 September, 2016    By - Dr Clemens
Unplanned, Postoperative Intubation in Pediatric Surgical Patients: Development and Validation of a Multivariable Prediction Model

Authors: Eric C. Cheon, M.D. et al Anesthesiology published on September 15, 2016. Background: To date, the independent predictors and outcomes of unplanned postoperative intubation (UPI) in pediatric patients after noncardiac surgery are yet to be characterized. The authors aimed to identify the incidence and predictors of this event and evaluated the effect of this event on […]

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Uncategorized Published - 19 September, 2016    By - Dr Clemens
The Effects of Fentanyl on Hepatic Mitochondrial Function

Anesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 311–325 AUTHORS: Djafarzadeh, Siamak PhD et al BACKGROUND: Remifentanil interferes with hepatic mitochondrial function. The aim of the present study was to evaluate whether hepatic mitochondrial function is affected by fentanyl, a more widely used opioid than remifentanil. METHODS: Human hepatoma HepG2 […]

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