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Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 535–546 AUTHORS: Mitrophanov, Alexander Y. PhD et al BACKGROUND: The use of prothrombin complex concentrates in trauma- and surgery-induced coagulopathy is complicated by the possibility of thromboembolic events. To explore the effects of these agents on thrombin generation (TG), we investigated combinations […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 570–577 AUTHORS: Fabbro, Michael II DO et al BACKGROUND: The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia […]
Read MoreA study published in PLOS ONE shows that symptoms of chronic fatigue syndrome can be provoked by imposing a mild to moderate strain to the muscles and nerves. The study included 80 individuals, 60 with CFS and 20 without CFS, who reported their levels of fatigue, body pain, lightheadedness, concentration difficulties, and headache every 5 […]
Read MoreHi. I’m Art Caplan, PhD from the Division of Medical Ethics and the New York University (NYU) Langone Medical Center. A former student of mine, who is now in medical school, asked me a question that comes up again and again. I have not talked about it here, but I think it does merit some […]
Read MoreAmong adults with opioid dependence maintaining abstinence with a stable dose of sublingual buprenorphine, the use of buprenorphine implants, compared with continued sublingual buprenorphine, did not result in an inferior likelihood of remaining a responder, according to a study published in the July 19 issue of JAMA. Opioid dependence is a growing public health concern […]
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