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Authors: Pierre Bouzat, M.D., Ph.D. et al Anesthesiology published on 5 2016. Background: To assess the performance of transcranial Doppler (TCD) in predicting neurologic worsening after mild to moderate traumatic brain injury. Methods: The authors conducted a prospective observational study across 17 sites. TCD was performed upon admission in 356 patients (Glasgow Coma Score [GCS], 9 to 15) […]
Read MoreA federal judge sentenced a 76-year-old physician to 25 years in prison for the deaths of three patients who overdosed on pain medications he prescribed, according to the Tampa Bay Times. The physician, Edward Neil Feldman, and his 66-year-old wife and office manager, Kim Feldman, were convicted during a February trial of financial conspiracy and of […]
Read MoreAuthors: Glenn S. Murphy, M.D. et al Anesthesiology 6 2016, Vol.124, 1246-1255. Background: Opportunities for anesthesia research investigators to obtain consent for clinical trials are often restricted to the day of surgery, which may limit the ability of subjects to freely decide about research participation. The aim of this study was to determine whether subjects providing same-day […]
Read MoreAnesthesia & Analgesia: April 13, 2016 AUTHORS: Djafarzadeh, Siamak PhD et al BACKGROUND: Remifentanil interferes with hepatic mitochondrial function. The aim of the present study was to evaluate whether hepatic mitochondrial function is affected by fentanyl, a more widely used opioid than remifentanil. METHODS: Human hepatoma HepG2 cells were exposed to fentanyl or pretreated with […]
Read MoreAnesthesia & Analgesia: April 13, 2016 AUTHORS: Sultan, Pervez MBChB, FRCA et al BACKGROUND: The intrathecal morphine dose achieving optimal analgesia for cesarean delivery while minimizing side effects has not yet been deduced. In this meta-analysis, our objective was to determine whether low- or high-dose intrathecal morphine provides acceptable duration and intensity of analgesia with […]
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