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Uncategorized Published - 2 February, 2017    By - Dr Clemens
Arterial Pressure Variation in Elective Noncardiac Surgery: Identifying Reference Distributions and Modifying Factors

Authors: Michael R. Mathis, M.D. et al Anesthesiology 2 2017, Vol.126, 249-259 Background: Assessment of need for intravascular volume resuscitation remains challenging for anesthesiologists. Dynamic waveform indices, including systolic and pulse pressure variation, are demonstrated as reliable measures of fluid responsiveness for mechanically ventilated patients. Despite widespread use, real-world reference distributions for systolic and pulse pressure variation […]

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Uncategorized Published - 2 February, 2017    By - Dr Clemens
Safety of Perioperative Glucocorticoids in Elective Noncardiac Surgery: A Systematic Review and Meta-analysis

Authors: Andrew J. Toner, F.R.C.A. et al       Anesthesiology 2 2017, Vol.126, 234-248. Background: Glucocorticoids are increasingly used perioperatively, principally to prevent nausea and vomiting. Safety concerns focus on the potential for hyperglycemia and increased infection. The authors hypothesized that glucocorticoids predispose to such adverse outcomes in a dose-dependent fashion after elective noncardiac surgery. Methods: The authors conducted […]

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Uncategorized Published - 2 February, 2017    By - Dr Clemens
Impact of Methylprednisolone on Postoperative Quality of Recovery and Delirium in the Steroids in Cardiac Surgery Trial: A Randomized, Double-blind, Placebo-controlled Substudy

Authors: Colin F. Royse, M.B.B.S., M.D., F.A.N.Z.C.A. et al   Anesthesiology 2 2017, Vol.126, 223-233. Background: Inflammation after cardiopulmonary bypass may contribute to postoperative delirium and cognitive dysfunction. The authors evaluated the effect of high-dose methylprednisolone to suppress inflammation on the incidence of delirium and postoperative quality of recovery after cardiac surgery. Methods: Five hundred fifty-five adults from […]

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Uncategorized Published - 2 February, 2017    By - Dr Clemens
Incidence of Connected Consciousness after Tracheal Intubation: A Prospective, International, Multicenter Cohort Study of the Isolated Forearm Technique

Authors: Robert D. Sanders, M.B.B.S., Ph.D., F.R.C.A. et al Anesthesiology 2 2017, Vol.126, 214-222. Background: The isolated forearm technique allows assessment of consciousness of the external world (connected consciousness) through a verbal command to move the hand (of a tourniquet-isolated arm) during intended general anesthesia. Previous isolated forearm technique data suggest that the incidence of connected consciousness […]

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Uncategorized Published - 1 February, 2017    By - Dr Clemens
“To Reverse or Not To Reverse?”: The Answer Is Clear!

Authors: Glenn S. Murphy, M.D. et al Anesthesiology 10 2016, Vol.125, 611-614 BY the late 1980s, it was well recognized that undetected postoperative residual neuromuscular block (PRNB) was a common occurrence in most postanesthesia care units (PACUs).1–4  However, an editorial in 1989 noted that there was little, if any, objective evidence to validate the hypothesis that PRNB […]

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