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Anesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 610–615 AUTHORS: Langford, Roger A. BMBS, FRCA et al BACKGROUND: We compared plasma and cerebrospinal fluid (CSF) pharmacokinetics of paracetamol after intravenous (IV) and oral administration to determine dosing regimens that optimize CSF concentrations. METHODS: Twenty-one adult patients were assigned randomly to […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 597–606 AUTHORS: Qiu, Chunyuan MD, MS et al BACKGROUND: In this article, we report on the implementation and impact of a Perioperative Surgical Home (PSH) model for the total knee arthroplasty at an integrated delivery system (Kaiser Permanente). METHODS: A multidisciplinary committee […]
Read MoreFor the antifibrinolytic agent tranexamic acid, doses varying between 5 and 15 mg/kg failed to produce a dose-dependent drop in hemoglobin after total knee (TKA) or total hip arthroplasty (THA), leading study investigators to recommend using the lowest of these doses in orthopedic patients. “At my institution, we reviewed quite a bit of data while […]
Read MoreContinuing a series begun last year, we asked D. John Doyle, MD, PhD, a member of the Anesthesiology News advisory board, to pose 7 questions to an international airway management roundtable, whose members he picked. The responses, including those of Dr Doyle, follow. John Doyle, MD, PhD Chief of General Anesthesiology Anesthesiology Institute Cleveland Clinic […]
Read MoreWith a new push to combat the opioid abuse epidemic, the Substance Abuse and Mental Health Services Administration (SAMHSA) has launched a new smartphone app providing essential resources for health care providers. The recent push to get more patients access to medication assisted treatment (MAT) for opioid addiction, and more doctors trained to provide it, […]
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