Authors: Viviane G. Nasr, MD et al Pediatr Crit Care Med. 2016;17(S1):S225-S231. Objectives: This review will focus on the pharmacokinetics (with an emphasis on the context-sensitive half-time), pharmacodynamics, and hemodynamic characteristics of the most commonly used sedative/hypnotic, analgesic, and IV anesthetics used in cardiac intensive care. In addition, the assessment of pain and agitation and withdrawal will […]
Read MoreAuthors: John W. Eikelboom, M.B.B.S. et al Anesthesiology 12 2016, Vol.125, 1121-1129. Background: The PeriOperative ISchemia Evaluation-2 (POISE-2) trial compared aspirin with placebo after noncardiac surgery. Methods: The authors randomly assigned 10,010 patients undergoing noncardiac surgery to receive 200 mg aspirin or placebo 2 to 4 h before surgery and then 100 mg aspirin daily or placebo daily […]
Read MoreAuthors: Hernández G et al., JAMA 2016 Oct 18; 316:1565 High-flow oxygen was noninferior to noninvasive positive pressure ventilation for preventing reintubation. During the last 2 years, we have seen a rapid rise in use of high-flow oxygen. Although its use is supported during the immediate postextubation period for patients at low risk for reintubation (NEJM JW […]
Read MoreAuthors: Ross A. Davenport, Ph.D. et al Anesthesiology published on November 17, 2016 Background: Major trauma is a leading cause of morbidity and mortality worldwide with hemorrhage accounting for 40% of deaths. Acute traumatic coagulopathy exacerbates bleeding, but controversy remains over the degree to which inhibition of procoagulant pathways (anticoagulation), fibrinogen loss, and fibrinolysis drive the pathologic process. […]
Read MoreThe U.S. Department of Health and Human Services (HHS) Office of Inspector General (OIG) has posted its Work Plan for FY2017. The 2017 Work Plan includes two issues specific to anesthesia care. These issues have been included in previous editions of the Work Plan. ASA members are reminded to be certain that they provide anesthesia services […]
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