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Uncategorized Published - 14 December, 2016    By - Dr Clemens
Impact of an Analgesia-Based Sedation Protocol on Mechanically Ventilated Patients in a Medical Intensive Care Unit

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 903–909 AUTHORS: Faust, Andrew C. PharmD, BCPS et al BACKGROUND: Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a “lighter” depth of sedation. Among these strategies are “analgosedation” protocols, which […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
The Feasibility of a Completely Automated Total IV Anesthesia Drug Delivery System for Cardiac Surgery

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 885–893 AUTHORS: Zaouter, Cedrick MD, MSc et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
Effect of Intraoperative Glucose Infusion on Catabolism of Adipose Tissue and Muscle Protein in Patients Anesthetized With Remifentanil in Combination With Sevoflurane During Major Surgery: A Randomized Controlled Multicenter Trial

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 869–876 AUTHORS: Sawada, Atsushi MD, PhD et al BACKGROUND: A harmful effect of stress hormone secretion during surgery is lipolysis and proteolysis to maintain normal blood glucose levels. A well-titrated general anesthetic improves blood glucose control by suppressing secretion of these stress […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
Targeted Coagulation Management in Severe Trauma: The Controversies and the Evidence

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 910–924 AUTHORS: Winearls, James BSc, MBBS, MRCP, FCICM et al Hemorrhage in the setting of severe trauma is a leading cause of death worldwide. The pathophysiology of hemorrhage and coagulopathy in severe trauma is complex and remains poorly understood. Most clinicians currently […]

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Uncategorized Published - 13 December, 2016    By - Dr Clemens
The Impact of Residual Neuromuscular Blockade, Oversedation, and Hypothermia on Adverse Respiratory Events in a Postanesthetic Care Unit: A Prospective Study of Prevalence, Predictors, and Outcomes

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 859–868 AUTHORS: Stewart, Paul A. MBBS, FANZCA et al BACKGROUND: Residual neuromuscular blockade (RNMB) has been linked to adverse respiratory events (AREs) in the postanesthetic care unit (PACU). However, these events are often not attributed to RNMB by anesthesiologists because they may […]

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