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Uncategorized Published - 23 December, 2016    By - Dr Clemens
Effects of Cardiopulmonary Bypass on Renal Perfusion, Filtration, and Oxygenation in Patients Undergoing Cardiac Surgery

Authors: Lukas Lannemyr, M.D. et al       Anesthesiology published on December 8, 2016. Background: Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass. The authors evaluated the effects of normothermic cardiopulmonary bypass on renal blood flow, glomerular filtration rate, renal oxygen consumption, and renal oxygen supply/demand relationship, i.e., renal oxygenation (primary outcome) in […]

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Uncategorized Published - 23 December, 2016    By - Dr Clemens
Arterial Pressure Variation in Elective Noncardiac Surgery: Identifying Reference Distributions and Modifying Factors

Authors: Michael R. Mathis, M.D. et al      Anesthesiology published on December 8, 2016 Background: Assessment of need for intravascular volume resuscitation remains challenging for anesthesiologists. Dynamic waveform indices, including systolic and pulse pressure variation, are demonstrated as reliable measures of fluid responsiveness for mechanically ventilated patients. Despite widespread use, real-world reference distributions for systolic and pulse […]

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Uncategorized Published - 23 December, 2016    By - Dr Clemens
Changes in Stroke Volume Induced by Lung Recruitment Maneuver Predict Fluid Responsiveness in Mechanically Ventilated Patients in the Operating Room

Authors: Matthieu Biais, M.D., Ph.D. et al       Anesthesiology published on December 8, 2016. Background: Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the magnitude of stroke volume reduction through lung recruitment maneuver could predict preload responsiveness. Methods: Twenty-eight mechanically ventilated patients with low tidal volume […]

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Uncategorized Published - 23 December, 2016    By - Dr Clemens
Intravenous Amisulpride for the Prevention of Postoperative Nausea and Vomiting: Two Concurrent, Randomized, Double-blind, Placebo-controlled Trials

Authors: Tong J. Gan, M.D. et al      Anesthesiology published on December 8, 2016. Background: Two essentially identical, randomized, double-blind, placebo-controlled, parallel-group phase III studies evaluated the efficacy of intravenous amisulpride, a dopamine D2/D3 antagonist, in the prevention of postoperative nausea and vomiting in adult surgical patients. Methods: Adult inpatients undergoing elective surgery during general anesthesia and having at […]

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Uncategorized Published - 22 December, 2016    By - Dr Clemens
Autism Gene Improves Understanding of Reduced Pain Sensitivity

Individuals with autism spectrum disorders (ASDs) are known to suffer from reduced pain sensitivity. New research suggests this phenomenon can be linked to a specific gene that may represent a critical avenue for future medications designed to treat chronic pain. By Thomas G. Ciccone   Patients with autism spectrum disorders (ASDs) are known to suffer from […]

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