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According to a new report, most criticisms of the CDC’s guidelines for opioid management of chronic noncancer pain did not include disclosures of any potential conflicts of interests with opioid manufacturers. Interviews with Caleb Alexander, MD, and Daniel B. Carr, MD In March of last year, the Centers for Disease Control and Prevention (CDC) released […]
Read MoreAuthors: Derek R. Laver, Ph.D. et al Anesthesiology 3 2017, Vol.126, 495-506. Background: Halogenated anesthetics activate cardiac ryanodine receptor 2–mediated sarcoplasmic reticulum Ca2+ release, leading to sarcoplasmic reticulum Ca2+ depletion, reduced cardiac function, and providing cell protection against ischemia-reperfusion injury. Anesthetic activation of ryanodine receptor 2 is poorly defined, leaving aspects of the protective mechanism uncertain. Methods: Ryanodine receptor 2 […]
Read MoreThe lack of pain specialists in many parts of the US has almost reached a crisis point, making the question of when and why to refer a patient especially timely. The recent Centers for Disease Control and Prevention (CDC) guidelines for opioid management suggest that clinicans should increase the frequency of follow-up visits when prescribing […]
Read MoreWhile well known as a significant factor in overall health, vitamin D deficiency could influence the occurrence of frequent headaches, especially in patients underexposed to sunlight. Given that dietary vitamin D has been identified in the development of various neurovascular diseases, such as neurocognitive decline and ischemic stroke,1,2 it was a matter of time before vitamin […]
Read MoreNew epidemiological evidence suggests that patients at greater risk of opioid abuse and misuse could be the same patients who are more likely to receive prescriptions for pain for an extended period of time. Interview with Patrick D. Quinn, PhD, and Robert J. Gatchel, PhD, ABPP With a rising rate of opioid prescribing among patients […]
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