Authors: Whiles BB et al., Crit Care Med 2017 Feb 6; In this study, earlier administration was associated with decreased progression to septic shock. Early antibiotics are associated with decreased mortality for patients with severe sepsis. To evaluate whether early administration of antibiotics is also associated with decreased progression to septic shock, investigators conducted a retrospective cohort […]
Read MoreAuthors: Drewry AM et al., Crit Care Med 2017 Feb 17; A meta-analysis showed that antipyretic therapy did not reduce 28-day mortality. Fever is certainly a sign of infection. But does treatment of fever improve outcomes in patients with sepsis? To find out, investigators conducted a meta-analysis of eight randomized trials (1507 patients) and six observational studies […]
Read MoreAuthors: Adam W. Amundson, M.D. et al Anesthesiology published on March 2, 2017. Background: Multimodal analgesia is standard practice for total knee arthroplasty; however, the role of regional techniques in improved perioperative outcomes remains unknown. The authors hypothesized that peripheral nerve blockade would result in lower pain scores and opioid consumption than two competing periarticular […]
Read MoreEdited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Migraine is associated with risk for stroke caused by cervical artery dissection, according to a JAMA Neurology study. Using a large Italian stroke registry, researchers studied nearly 2500 adults aged 18 to 45 who experienced a first ischemic stroke; 13% had spontaneous cervical […]
Read MoreA review and retrospective study on the effectiveness of scrambler (stimulation) therapy to reduce noncancer-related neuropathic pain syndromes, with apparent, maximal pain relief achieved at 1 to 2 weeks. By Alexandra M. Lesenskyj, Christina R. Maxwell, PhD, MTR and Ricardo A. Cruciani, MD, PhD Minimizing the incidence of medication dependence in patients with chronic neuropathic […]
Read More