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Authors: Panwar R et al. Am J Respir Crit Care Med 2016 Jan 1. Targeting to 88%–92% did not cause harm. The optimal oxygenation goal for patients who are receiving invasive mechanical ventilation remains unclear. Clinicians usually target resolution of hypoxemia and pay little attention to weaning levels of oxygen once 100% saturation has been achieved. However, harms […]
Read MoreAUTHORS: Richardson, Michael G. MD et Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 548–553 BACKGROUND: Evidence on the analgesic effectiveness of nitrous oxide for labor pain is limited. Even fewer studies have looked at patient satisfaction. Although nitrous oxide appears less effective than neuraxial analgesia, it is unclear whether labor […]
Read MoreAUTHORS: Vanda G. MD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 438–444 BACKGROUND: Haloperidol is an antipsychotic. At low doses, it is a useful agent for the prophylaxis of postoperative nausea and vomiting (PONV). However, its use for treating established PONV has not been well studied. METHODS: This […]
Read MoreAUTHORS: Kopec, Michael MD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 398–405 BACKGROUND: This study sought to determine whether preoperatively measured high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) improve cardiac risk prediction in patients undergoing major noncardiac surgery compared with the standard risk indices. METHODS: […]
Read MoreProlonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen modestly increases the risk for hearing loss in older women, a prospective analysis of data from the Nurses’ Health Study (NHS) I has found. A similar relationship was not seen with aspirin. The effect may not be large, but “given the high prevalence of analgesic use, […]
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