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Uncategorized Published - 24 June, 2025    By - Dr Clemens
Systemic Risks of Topical Anesthetics in Barrier-Compromised Dermatologic Patients

Authors: George Chamoun et al Cureus 17(5): e84157. doi:10.7759/cureus.84157 Abstract Topical anesthetics are widely employed in dermatology for cosmetic interventions, laser therapies, and minor surgical procedures. Although generally safe, their systemic absorption is highly influenced by the integrity of the epidermal barrier. Inflammatory skin disorders such as psoriasis and atopic dermatitis compromise the stratum corneum […]

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Uncategorized Published - 24 June, 2025    By - Dr Clemens
Ketamine-induced sustained modulation of GABAA receptor function in mouse hippocampal neurons following anesthesia

Authors: Wang, Dian-Shi M.D., Ph.D et al Anesthesiology ():10.1097/ALN.0000000000005595, June 09, 2025. Background: Excess function of GABAA receptors that generate a tonic inhibitory conductance contributes to postanesthetic cognitive impairment. Ketamine may have postoperative cognition-sparing properties; however, whether it reduces excess GABAA receptor function is unknown. This study investigated whether ketamine prevents a sustained anesthetic-triggered increase in GABAA receptor function in […]

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Uncategorized Published - 24 June, 2025    By - Dr Clemens
Psychological Effects of Explicit Recall under Sedation and after Surgery (PEERS)

Authors: Chui, Jason MBChB et al Anesthesiology ():10.1097/ALN.0000000000005603, June 09, 2025. Background: Explicit recall occurring during sedation/regional anaesthesia is common but has long been assumed to have no sequelae. We conducted a prospective cohort study to determine the incidence of explicit recall experience under sedation/regional anaesthesia, as well as, to assess the recall experiences that are […]

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Uncategorized Published - 24 June, 2025    By - Dr Clemens
A pharmacist-partnered opioid tapering service before total hip or knee arthroplasty: Qualitative analysis of patient counselling sessions

Authors: Young, Sophie A. BPharm(Hons) et a; Anesthesiology ():10.1097/ALN.0000000000005594, June 06, 2025. Background Currently, no literature on patients’ experiences with opioid tapering before elective surgery has been published. Recent evidence indicates tapering opioids before total hip or knee arthroplasty improves post-surgical outcomes. This study qualitatively analyzed consultation sessions of patients receiving a pharmacist-partnered opioid tapering service […]

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Uncategorized Published - 24 June, 2025    By - Dr Clemens
When Words Fail: Bridging the Gap in Pain Management for Limited English Proficiency Patients

Authors: Abdelmessih, Beshoy A. MD; Iasiello, Jack MD Anesthesia & Analgesia 140(6):p e75-e76, June 2025. To the Editor Please find attached our letter titled “When Words Fail: Bridging the Gap in Pain Management for Limited English Proficiency Patients” in response to the article, “Differences in Acute Postoperative Opioid Use by English Proficiency, Race, and Ethnicity […]

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