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Uncategorized Published - 27 June, 2017    By - Dr Clemens
Reversal of Vecuronium-induced Neuromuscular Blockade with Low-dose Sugammadex at Train-of-four Count of Four: A Randomized Controlled Trial

Authors: László Asztalos, M.D. et al Anesthesiology published on June 22, 2017 Background: Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg. We investigated whether these doses of sugammadex can also reverse vecuronium at a similar level of block. Methods: Sixty-five patients were randomly assigned, and […]

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Uncategorized Published - 27 June, 2017    By - Dr Clemens
Extubation Success Prediction in a Multicentric Cohort of Patients with Severe Brain Injury

Authors: Karim Asehnoune, M.D., Ph.D. et al Anesthesiology published on June 22, 2017 Background: Patients with brain injury are at high risk of extubation failure. Methods: We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in […]

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Uncategorized Published - 27 June, 2017    By - Dr Clemens
Investigational Injectable Buprenorphine Shows Promise for Opioid Use Disorder

A weekly injectable depot formulation of buprenorphine may be effective in treating opioid use disorder, according to a small, industry-funded, phase II trial published in JAMA Psychiatry. Currently, sublingual buprenorphine can be diverted and misused. Fifty patients with opioid use disorder who weren’t seeking treatment were randomized to receive two 24- or 32-mg doses of injectable […]

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Uncategorized Published - 26 June, 2017    By - Dr Clemens
Utilizing Forced Vital Capacity to Predict Low Lung Compliance and Select Intraoperative Tidal Volume During Thoracic Surgery.

AUTHORS: Hoftman, Nir MD et al Anesthesia & Analgesia: March 8, 2017 BACKGROUND: Tidal volume selection during mechanical ventilation utilizes dogmatic formulas that only consider a patient’s predicted body weight (PBW). In this study, we investigate whether forced vital capacity (FVC) (1) correlates better to total lung capacity (TLC) than PBW, (2) predicts low pulmonary compliance, […]

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Uncategorized Published - 26 June, 2017    By - Dr Clemens
Risk Factors for Severe Postpartum Hemorrhage After Cesarean Delivery: Case-Control Studies

AUTHORS: Butwick, Alexander J. MBBS, FRCA, MS et al Anesthesia & Analgesia: March 8, 2017 BACKGROUND: Women who undergo intrapartum caesarean delivery (CD) are at increased risk of postpartum hemorrhage (PPH) compared with those undergoing prelabor CD. To determine whether the presence and strength of the associations between individual risk factors and severe PPH vary among […]

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