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Uncategorized Published - 7 July, 2017    By - Dr Clemens
Measuring Clinically Meaningful Outcomes in Chronic Pain Clinical Trials

Current recommendations for outcome measures in clinical trials for chronic pain were outlined. Standardized and clinically meaningful outcome measures in clinical trials in chronic pain may enhance efforts to develop effective treatments for chronic pain patients. Diane Flynn, MD, MPH, from Madigan Army Medical Center, outlined the current recommendations for outcome measures in clinical trials […]

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Uncategorized Published - 6 July, 2017    By - Dr Clemens
Lower Education Level Is Associated with Higher Risk for Cardiovascular Disease

Authors: Adler NE and Glymour M., JAMA Intern Med 2017 Jun 12; More than half of adults who didn’t complete high school had adverse CV events during their lifetimes. Educational attainment is associated with risk for cardiovascular disease (CVD), presumably as a marker or mediator of other traditional risk factors. To clarify the magnitude of this risk, […]

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Uncategorized Published - 6 July, 2017    By - Dr Clemens
How Stable Are Patients with Moderate Aortic Stenosis and Left Ventricular Dysfunction?

Authors: WJ., J Am Coll Cardiol 2017 May 16; 69:2393 A high rate of adverse events prompts the question of whether earlier intervention would improve outcomes. The authors of this international, four-site study examined longitudinal outcomes data on 305 patients (mean age, 73; 75% men) who were identified on baseline echocardiograms with moderate aortic stenosis (AS; defined […]

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Uncategorized Published - 6 July, 2017    By - Dr Clemens
Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II (ENIGMA II) Revisited: Patients Still Vomiting

Authors: Edmond C. K. Li, M.D. et al Anesthesiology 7 2017, Vol.127, 204-205. To the Editor: We read the secondary analysis of the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II (ENIGMA II) trial for severe postoperative nausea and vomiting (PONV) with great interest.1 Because PONV remains an often-cited risk in using nitrous oxide,2 the […]

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Uncategorized Published - 6 July, 2017    By - Dr Clemens
Low-Dose Aspirin Beginning Early in Pregnancy Helps Prevent Preterm Preeclampsia

Use of low-dose aspirin lowers the risk for preeclampsia among women determined to be at high risk during first-trimester screening, according to a study presented at a meeting of the Fetal Medicine Foundation and published in the New England Journal of Medicine. Over 1700 high-risk women with singleton pregnancies were randomized to receive 150-mg aspirin or […]

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