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Although the mechanisms underlying the development and maintenance of neuropathic pain are still poorly understood, both µ-opioid and NMDA receptors have been implicated. A randomized controlled trial investigating treatments for chronic neuropathic pain revealed that a ketamine regimen is superior to methadone, or ketamine combined with methadone, in alleviating neuropathic pain and associated sensory changes.1 […]
Read MoreIn patients with migraine, structural and functional changes occur in brain regions that are not directly involved in processing pain signals, such as the striatum or basal ganglia. Acute migraine attacks are associated with a reduction in dopamine release, according to a study published in Neurology.1 In patients with migraine, structural and functional changes occur in […]
Read MoreThe minimum criteria for informed consent (IC) are being met in pediatric anesthesia, but more can be done to obtain explicit agreement from patients’ parents, according to a prospective, cross-sectional study conducted at Seattle Children’s Hospital, in Washington. The findings come from analyses of recorded and transcribed conversations between parents of surgical patients aged 1 […]
Read MoreIf the experience of researchers at Duke University Medical Center is indicative of the nation as a whole, then infused medications are being wasted throughout the perioperative process. This is the product of preparing and priming standard infusions regardless of patient and procedural characteristics. The good news is that such practices seem to be easily […]
Read MoreA majority of institutions do not have a written policy for mechanical ventilation during intrahospital transport of children with congenital heart disease. That was the finding from a survey of pediatric anesthesia program directors throughout North America. Presented at the 2017 meeting of the Society for Pediatric Anesthesia/American Academy of Pediatrics Section on Anesthesiology and […]
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