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Uncategorized Published - 30 August, 2017    By - Dr Clemens
Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room

Authors: Matthieu Biais, M.D., Ph.D. et al Anesthesiology 9 2017, Vol.127, 450-456 Background: Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the effects of 250 ml crystalloid in mechanically […]

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Uncategorized Published - 29 August, 2017    By - Dr Clemens
Left Lateral Table Tilt for Elective Cesarean Delivery under Spinal Anesthesia Has No Effect on Neonatal Acid–Base Status: A Randomized Controlled Trial

Authors: Allison J. Lee, M.D. Background: Current recommendations for women undergoing cesarean delivery include 15° left tilt for uterine displacement to prevent aortocaval compression, although this degree of tilt is practically never achieved. We hypothesized that under contemporary clinical practice, including a crystalloid coload and phenylephrine infusion targeted at maintaining baseline systolic blood pressure, there would […]

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Uncategorized Published - 29 August, 2017    By - Dr Clemens
Opioid Plus Psychotropic Drug Use in Pregnancy Tied to Greater Risk for Neonatal Drug Withdrawal

Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Concurrent prescription of psychotropic medications and opioids in pregnant women may put their infants at increased risk for neonatal drug withdrawal, according to a study in The BMJ. Using Medicaid data, researchers studied over 200,000 women who were prescribed opioids in the last 45 days of […]

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Uncategorized Published - 29 August, 2017    By - Dr Clemens
Could Greater Depth of ED Sedation Be Associated with Worse Outcome?

Authors: Stephens RJ et al., Chest 2017 Jun 29; In a prospective study of mechanically ventilated emergency department patients, deeper sedation levels were associated with increased mortality. Deeper sedation levels within the first 48 hours of intensive care unit admission have been associated with longer duration of mechanical ventilation and increased mortality. Unclear, however, is whether deeper […]

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Uncategorized Published - 29 August, 2017    By - Dr Clemens
Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial

Authors: Jacqueline M. Leung, M.D., M.P.H. et al Anesthesiology published on July 20, 2017 Background: Postoperative pain and opioid use are associated with postoperative delirium. We designed a single-center, randomized, placebo-controlled, parallel-arm, double-blinded trial to determine whether perioperative administration of gabapentin reduced postoperative delirium after noncardiac surgery. Methods: Patients were randomly assigned to receive placebo (N = 347) […]

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