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Uncategorized Published - 1 November, 2017    By - Dr Clemens
Muscle Relaxation and Lower Airway Characteristics May Affect Tidal Volume during Pressure-controlled Ventilation

Authors: Zhiqiang Zhou, M.D.; Xueren Wang, M.D., Ph.D. Anesthesiology 11 2017, Vol.127, 896. doi:10.1097/ALN.0000000000001826 To the Editor: With great interest, we read the article by Sato et al.,1  which reported the effect of sleep-disordered breathing on tidal volume with mask ventilation during anesthetic induction. Additional details might better clarify this study and affect the interpretation of the results. The […]

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Uncategorized Published - 1 November, 2017    By - Dr Clemens
Effect of Bronchoconstriction-induced Ventilation–Perfusion Mismatch on Uptake and Elimination of Isoflurane and Desflurane

Authors: Moritz Kretzschmar, M.D., Ph.D., D.E.S.A. et al Anesthesiology 11 2017, Vol.127, 800-812. Background: Increasing numbers of patients with obstructive lung diseases need anesthesia for surgery. These conditions are associated with pulmonary ventilation/perfusion (VA/Q) mismatch affecting kinetics of volatile anesthetics. Pure shunt might delay uptake of less soluble anesthetic agents but other forms of VA/Q scatter have […]

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Uncategorized Published - 1 November, 2017    By - Dr Clemens
Clinical Effectiveness of Intravenous Exenatide Infusion in Perioperative Glycemic Control after Coronary Artery Bypass Graft Surgery: A Phase II/III Randomized Trial

Authors: Guillaume Besch, M.D. et Anesthesiology 11 2017, Vol.127, 775-787. Background: We aimed to assess the clinical effectiveness of intravenous exenatide compared to insulin in perioperative blood glucose control in coronary artery bypass grafting surgery patients. Methods: Patients more than 18 yr old admitted for elective coronary artery bypass grafting were included in a phase II/III nonblinded randomized […]

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Uncategorized Published - 1 November, 2017    By - Dr Clemens
Precision Correction of Coagulopathy or Prothrombin Complex Concentrates?: Reversal Options for Dabigatran following Trauma

Authors: Matthew D. Neal, M.D. et al Anesthesiology 11 2017, Vol.127, 744-746. EMERGENCY care providers need to have therapies for the acutely bleeding patient, especially for trauma patients and those requiring emergency surgery. Trauma is a leading cause of mortality worldwide with hemorrhage as the leading cause of preventable death. As many as 30% of severely […]

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Uncategorized Published - 1 November, 2017    By - Dr Clemens
Promoting Safety, Quality, and Value through Patient Blood Management

Author: Jonathan H. Waters, M.D. Anesthesiology 11 2017, Vol.127, 738-740. “…this report highlights the role that an anesthesiologist can play in leading patient blood management.” IN this issue of Anesthesiology is a report on the next evolution of a patient blood management program.1  This report explores what was done at the Johns Hopkins Health System to take a […]

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