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Uncategorized Published - 31 January, 2018    By - Dr Clemens
Simple Pre-Op Breathing Intervention Reduces Post-Op Lung Complications

Brief training in breathing exercises before upper abdominal surgery significantly reduces postoperative pulmonary complications, a study in The BMJ finds. Over 400 adults scheduled for surgery (e.g., colectomy, nephrectomy) were randomized to a breathing exercise intervention or a control group. All patients received, within 6 weeks before surgery, an information booklet that prescribed postoperative breathing exercises. Intervention […]

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Uncategorized Published - 30 January, 2018    By - Dr Clemens
Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock

Authors: Michelle Trieu, B.Sc. et al Anesthesiology 2 2018, Vol.128, 361-374. Background: Microcirculatory dysfunction is associated with multiple organ failure and unfavorable patient outcome. We investigated whether therapeutically targeting the endothelial angiopoietin/Tie2 system preserves microvascular integrity during hemorrhagic shock. Methods: Rats were treated with the angiopoietin-1 mimetic vasculotide and subjected to hemorrhagic shock and fluid resuscitation. Microcirculatory perfusion […]

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Uncategorized Published - 30 January, 2018    By - Dr Clemens
Cyclosporine before Coronary Artery Bypass Grafting Does Not Prevent Postoperative Decreases in Renal Function: A Randomized Clinical Trial

Authors: Per Ederoth, M.D., Ph.D. et al Anesthesiology published on January 24, 2018. Background: Acute kidney injury is a common complication after cardiac surgery, leading to increased morbidity and mortality. One suggested cause for acute kidney injury is extracorporeal circulation–induced ischemia–reperfusion injury. In animal studies, cyclosporine has been shown to reduce ischemia–reperfusion injury in the kidneys. […]

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Uncategorized Published - 30 January, 2018    By - Dr Clemens
Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature: A Factorial Randomized Trial

Authors: Lijian Pei, M.D. et al Anesthesiology published on January 24, 2018. Background: The effect of ambient temperature, with and without active warming, on intraoperative core temperature remains poorly characterized. The authors determined the effect of ambient temperature on core temperature changes with and without forced-air warming. Methods: In this unblinded three-by-two factorial trial, 292 adults were randomized […]

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Uncategorized Published - 30 January, 2018    By - Dr Clemens
Do You Trust the Medical Profession?

By Dhruv Khullar A growing distrust could be dangerous to public health and safety. Trust is crucial in the relationship between patients and health care providers, but it’s been on the decline in recent decades.CreditJustin Sullivan/Getty Images Trust, in each other and in American institutions, is vital for our social and economic well-being: It allows us […]

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