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Uncategorized Published - 20 February, 2018    By - Dr Clemens
Prediction of Bispectral Index during Target-controlled Infusion of Propofol and Remifentanil: A Deep Learning Approach

Authors: Hyung-Chul Lee, M.D. et al Anesthesiology 3 2018, Vol.128, 492-501. doi:10.1097/ALN.0000000000001892 Background: The discrepancy between predicted effect-site concentration and measured bispectral index is problematic during intravenous anesthesia with target-controlled infusion of propofol and remifentanil. We hypothesized that bispectral index during total intravenous anesthesia would be more accurately predicted by a deep learning approach. Methods: Long short-term memory […]

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Uncategorized Published - 20 February, 2018    By - Dr Clemens
Association of Hospital-level Neuraxial Anesthesia Use for Hip Fracture Surgery with Outcomes: A Population-based Cohort Study

Authors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. et al Anesthesiology 3 2018, Vol.128, 480-491. Background: There is consistent and significant variation in neuraxial anesthesia use for hip fracture surgery across jurisdictions. We measured the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival (primary outcome) and length of stay and costs (secondary […]

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Uncategorized Published - 19 February, 2018    By - Dr Clemens
Do Anesthetic Choices Signal Quality?

Authors: Catherine L. Chen, M.D., M.P.H. et al Anesthesiology 3 2018, Vol.128, 429-430. HOW does one identify high-quality anesthetic care? Although the specialty of anesthesiology has succeeded in improving the safety and quality of care over time, with a 97% reduction in anesthesia-related deaths between 1948 and 2005, from 3.3 per 100,000 population to 1.1 per […]

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Uncategorized Published - 19 February, 2018    By - Dr Clemens
Opioid Use Tied to Risk for Invasive Pneumococcal Disease

Current use of prescription opioids is associated with increased risk for invasive pneumococcal disease (IPD), suggests an Annals of Internal Medicine study. Researchers studied Tennessee patients who’d filled an opioid prescription between 1995 and 2014. Of these, they compared 1200 patients with an IPD diagnosis with 24,000 controls without IPD. After multivariable adjustment, current opioid use was […]

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Uncategorized Published - 19 February, 2018    By - Dr Clemens
Anaemia and red blood cell transfusion in intracranial neurosurgery: a comprehensive review

Authors: A. Kisilevsky et al British Journal of Anesthesia February 2018 Summary Both anaemia and blood transfusion are associated with poor outcomes in the neurosurgical population. Based on the available literature, the optimal haemoglobin concentration for neurologically injured patients appears to be in the range of 9.0–10.0 g dl−1, although the individual risks and benefits […]

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