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AUTHORS: Rousseau-Saine, Nicolas MD et al Anesthesia & Analgesia: March 2018 – Volume 126 – Issue 3 – p 1019–1027 BACKGROUND: Total knee arthroplasty (TKA) reduces knee extensor muscle strength (KES) in the operated limb for several months after the surgery. Immediately after TKA, compared to either inguinal femoral nerve block or placebo, adductor canal block (ACB) […]
Read MoreAUTHORS: Kalra, Rajat MBChB et al Anesthesia & Analgesia: March 2018 – Volume 126 – Issue 3 – p 867–875 BACKGROUND: Targeted temperature management (TTM) with therapeutic hypothermia is an integral component of postarrest care for survivors. However, recent randomized controlled trials (RCTs) have failed to demonstrate the benefit of TTM on clinical outcomes. We sought to […]
Read MoreNow in Phase III Trials: An investigational agent designed to improve conventional opioid pharmacology has demonstrated efficacy and safety, as well as faster onset of action, in a pair of pivotal trials. Compared with placebo, patients receiving IV oliceridine (Olinvo, Trevena), a G protein-biased ligand (GPBL) at the mu-opioid receptor, experienced superior relief following bunionectomy or abdominoplasty. Oliceridine also showed favorable […]
Read MoreI just thought this was interesting so I wanted to share it with our readers Some 7% of U.S. women who gave birth in 2016 smoked while they were pregnant, according to new data from the CDC’s National Center for Health Statistics. The analysis was based on birth certificate data for all U.S. births that […]
Read MoreAUTHORS: Richards, Justin E. MD et al Anesthesia & Analgesia: March 2018 – Volume 126 – Issue 3 – p 904–910 BACKGROUND: Early hyperglycemia is associated with multiple organ failure (MOF) after traumatic injury; however, few studies have considered the contribution of depth of clinical shock. We hypothesize that when considered simultaneously, glucose and lactate are associated […]
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