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Uncategorized Published - 21 March, 2018    By - Dr Clemens
Prolonged Catheter Use and Infection in Regional Anesthesia: A Retrospective Registry Analysis

Authors: Hagen Bomberg, M.D. et al Anesthesiology 4 2018, Vol.128, 764-773. Background: Prolonged catheter use is controversial because of the risk of catheter-related infection, but the extent to which the risk increases over time remains unknown. We thus assessed the time-dependence of catheter-related infection risk up to 15 days. Methods: Our analysis was based on the German Network […]

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Uncategorized Published - 20 March, 2018    By - Dr Clemens
Association of Hospital-level Neuraxial Anesthesia Use for Hip Fracture Surgery with Outcomes: A Population-based Cohort Study

Authors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. et al Anesthesiology 3 2018, Vol.128, 480-491. Background: There is consistent and significant variation in neuraxial anesthesia use for hip fracture surgery across jurisdictions. We measured the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival (primary outcome) and length of stay and costs (secondary […]

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Uncategorized Published - 20 March, 2018    By - Dr Clemens
Dopamine D2-receptor Antagonist Droperidol Deepens Sevoflurane Anesthesia

Authors: Ryuhei Araki, M.D.et al Anesthesiology 4 2018, Vol.128, 754-763. Background: Although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine D2 receptor antagonism in humans. This study examined the effect of the D2 receptor antagonist droperidol on sevoflurane anesthesia by examining α and […]

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Uncategorized Published - 20 March, 2018    By - Dr Clemens
Effect of Epidural Infusion Bolus Delivery Rate on the Duration of Labor Analgesia: A Randomized Clinical Trial

Authors: Elizabeth M. S. Lange, M.D. et al Anesthesiology 4 2018, Vol.128, 745-753 Background: Programmed intermittent boluses of local anesthetic have been shown to be superior to continuous infusions for maintenance of labor analgesia. High-rate epidural boluses increase delivery pressure at the catheter orifice and may improve drug distribution in the epidural space. We hypothesized that high-rate […]

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Uncategorized Published - 20 March, 2018    By - Dr Clemens
18F-florbetapir Positron Emission Tomography–determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

Authors: Rebecca Y. Klinger, M.D., M.S. et al Anesthesiology 4 2018, Vol.128, 728-744. Background: Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by 18F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively. Methods: Amyloid deposition was evaluated in cardiac […]

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